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Incontinence: Trigonal injection of botulinum toxin-A improves outcome.

机译:失禁:三角注射肉毒杆菌毒素A可改善结局。

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摘要

Second-line treatment of neurogenic bladder typically consists of a botulinum toxin-A (BTX-A) injection directly into the detrusor. New data, however, from a study carried out by Taha Abdel-Meguid at Abdulaziz University Hospital in Jeddah, Saudi Arabia, suggest that including the trigone in the injection protocol can significantly improve short-term results. "The trigone is known to be extensively innervated and its smooth muscles are very sensitive to small changes in pressure," explains Abdel-Meguid. "In clinical practice, many of our patients with overactive bladder describe prompt urgency and/or urinary incontinence on rising from a sitting to standing position, further implicating involvement of the trigone in these symptoms."
机译:神经源性膀胱的二线治疗通常包括将肉毒杆菌毒素A(BTX-A)直接注入逼尿肌。然而,来自沙特阿拉伯吉达的阿卜杜勒阿齐兹大学医院的Taha Abdel-Meguid进行的一项研究得出的新数据表明,将Trigone纳入注射方案可以显着改善短期疗效。 Abdel-Meguid解释说:“众所周知,三角骨广泛受神经支配,其平滑肌对微小的压力变化非常敏感。” “在临床实践中,我们的许多膀胱过度活动症患者从坐位上升到站立位时都表现出急迫性尿急和/或尿失禁,这进一步暗示三角骨与这些症状有关。”

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