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Benefit and safety of adjuvant radiation therapy

机译:辅助放射治疗的益处和安全性

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Approximately 35% of patients undergoing a radical prostatectomy for prostate cancer will experience biochemical recurrence within 10 years of surgery. High Gleason score, extracapsular extension, seminal vesicle invasion, and positive surgical margins have all been identified as risk factors for post-prostatectomy recurrence. Several studies have shown that patients with unfavourable prognostic factors are at increased risk of local and distant failure after prostatectomy, suggesting that these patients would derive particular benefit from postoperative radiotherapy. The rationale for adjuvant radiotherapy is based on several factors.
机译:大约35%的接受前列腺癌根治性前列腺切除术的患者将在手术10年内经历生化复发。高格里森评分,囊外延伸,精囊侵犯和手术切缘阳性均已被确定为前列腺切除术后复发的危险因素。几项研究表明,预后不良的患者前列腺切除术后局部和远距离衰竭的风险增加,这表明这些患者将从术后放疗中受益。辅助放疗的基本原理基于几个因素。

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