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Prostate cancer: Surgery versus observation for localized prostate cancer

机译:前列腺癌:局部前列腺癌的手术与观察

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Bill-Axelson et al.1 recently published an update of the Scandinavian Prostate Cancer Group Study Number 4 (SPCG-4), one of the key clinical trials in localized prostate cancer treatment. Almost two-thirds of the 695 participants enrolled in this trial and randomly allocated to undergo radical prostatectomy or watchful waiting between 1989 and 1999 had died by the end of 2012. Inclusion criteria were the presence of clinically localized, well-differentiated or moderately well-differentiated prostate cancer, age <75 years, life expectancy >10 years, serum PSA level <50ng/ml, no metastases on bone scan, no upper urinary tract obstruction and no other malignancies.
机译:Bill-Axelson等人1最近发表了斯堪的纳维亚前列腺癌研究组第4号(SPCG-4)的更新,这是局部前列腺癌治疗中的关键临床试验之一。参加该试验的695名参与者中,几乎有三分之二于1989年至1999年间接受了前列腺癌根治术或观察性等待,直到2012年底死亡。纳入标准是存在临床上局部的,分化良好或中等程度的-分化型前列腺癌,年龄<75岁,预期寿命> 10年,血清PSA水平<50ng / ml,骨扫描无转移,无上尿路梗阻,无其他恶性肿瘤。

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