Prostate cancer: New insight into mechanisms of castration resistance.

Payton S

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Prostate cancer: New insight into mechanisms of castration resistance.

机译：前列腺癌：对去势抵抗机制的新见解。

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Constitutively active androgen receptor splice variants (ARVs) have been implicated in the progression of prostate cancer to a castration-resistant state. Two new papers add to our understanding of how this might occur, highlighting the involvement of full-length androgen receptor (AR).

机译：组成型活性雄激素受体剪接变体（ARV）与前列腺癌发展为去势抵抗状态有关。有两篇新论文加深了我们对这可能如何发生的理解，强调了全长雄激素受体（AR）的参与。

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《Nature reviews. Urology》 |2010年第11期|共1页
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Payton S;
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中图分类泌尿科学（泌尿生殖系疾病）;
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1. Prostate cancer: New insight into mechanisms of castration resistance. [J] . Payton S Nature reviews. Urology . 2010,第11期

机译：前列腺癌：对去势抵抗机制的新见解。
2. Prostate radiation in non-metastatic castrate refractory prostate cancer provides an interesting insight into biology of prostate cancer [J] . Abigail C Pascoe, Santhanam Sundar Radiation oncology . 2012,第1期

机译：非转移性去势难治性前列腺癌中的前列腺辐射为前列腺癌生物学提供了有趣的见解
3. Can targeting the androgen receptor in localized prostate cancer provide insights into why men with metastatic castration-resistant prostate cancer die? [J] . SmallE.J. Journal of Clinical Oncology . 2014,第33期

机译：靶向雄激素受体的局部前列腺癌能否提供洞悉为何具有去势去势抵抗性前列腺癌的男性死亡的原因？
4. Androgen Receptor Deregulation and the Transition to Castration Resistance in Prostate Cancer: Mechanisms and Potential Therapeutic Implications [C] . Karen E. Knudsen Genitourinary Cancers Symposium . 2011

机译：雄激素受体放松调节和前列腺癌抗阉割性的过渡：机制和潜在的治疗意义
5. Mechanism of Extracellular Matrix Induced Tumor Survival and Drug Resistance in Castration-Resistant Prostate Cancer [D] . Chaudhary, Pooja. 2019

机译：细胞外基质诱导肿瘤存活和抗阉割前列腺癌的耐药机制
6. Prostate radiation in non-metastatic castrate refractory prostate cancer provides an interesting insight into biology of prostate cancer [O] . Abigail C Pascoe, Santhanam Sundar 2012

机译：非转移性去势难治性前列腺癌中的前列腺辐射为前列腺癌的生物学研究提供了有趣的见解
7. Prostate radiation in non-metastatic castrate refractory prostate cancer provides an interesting insight into biology of prostate cancer [O] . Abigail C Pascoe, Santhanam Sundar 2012

机译：非转移性去势难治性前列腺癌中的前列腺辐射为前列腺癌的生物学研究提供了有趣的见解
8. Understanding and Targeting Tumor Microenvironment in Prostate Cancer to Inhibit Tumor Progression and Castration Resistance. [R] . Lu, X. 2016

机译：了解和靶向前列腺癌中的肿瘤微环境抑制肿瘤进展和去势抵抗。

Prostate cancer: New insight into mechanisms of castration resistance.

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