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The emerging role of diffusion-weighted MRI in prostate cancer management

机译:弥散加权MRI在前列腺癌管理中的新兴作用

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A significant amount of research has focused on the role of diffusion-weighted MRI (DW-MRI) in the management of patients with prostate cancer. Although uncertainties remain, a clearer picture of where this technique fits into clinical practice is now available. A combination of DW-MRI and T2-weighted MRI (T2W-MRI) demonstrates improved accuracy for lesion detection and localization compared with T2W-MRI alone, and has been suggested as a tool to guide tissue biopsy. DW-MRI could also have roles in active surveillance, evaluating treatment efficacy, and predicting disease recurrence. Furthermore, DW-MRI offers the exciting possibility of gathering information about tumor characteristics and aggressiveness in a noninvasive manner. Validation in large prospective multicenter trials is critical if this technique is to be integrated into current management algorithms for prostate cancer.
机译:大量研究集中在扩散加权MRI(DW-MRI)在前列腺癌患者管理中的作用。尽管不确定性仍然存在,但现在可以更清楚地了解该技术在临床实践中的适用范围。与单独的T2W-MRI相比,DW-MRI和T2加权MRI(T2W-MRI)的结合显示了更高的病变检测和定位准确性,并已被建议作为指导组织活检的工具。 DW-MRI还可以在主动监视,评估治疗效果和预测疾病复发中发挥作用。此外,DW-MRI提供了令人兴奋的可能性,可以以非侵入性方式收集有关肿瘤特征和侵袭性的信息。如果要将这项技术集成到当前的前列腺癌管理算法中,那么在大型前瞻性多中心试验中进行验证至关重要。

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