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首页> 外文期刊>Nature reviews. Urology >Prostate cancer: Anterior perirectal fat: a barrier to optimal outcomes in patients undergoing HIFU therapy.
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Prostate cancer: Anterior perirectal fat: a barrier to optimal outcomes in patients undergoing HIFU therapy.

机译：前列腺癌：直肠前脂肪：接受HIFU治疗的患者获得最佳结局的障碍。

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High-intensity focused ultrasound (HIFU) is a relatively new treatment for men with prostate cancer, which is less invasive than the gold standard of prostatectomy. It involves coagulation and ablation of tumor using focused ultrasound beams generated within a rectal probe. While obesity is associated with unfavorable pathologic features and an increased risk of biochemical recurrence following radical prostatectomy, the effects of high BMI in men undergoing HIFU are not known. An increased amount of anterior perirectal fat tissue (APFT) between the ultrasound probe and the target prostate tissue might act like a shield, reflecting the ultrasound waves and preventing full coverage of the focal lesion. Sumitomo and colleagues performed a retrospective analysis of data from 115 Japanese patients to determine whether this measure of obesity is associated with decreased disease-free survival following HIFU.
机译：高强度聚焦超声（HIFU）是前列腺癌男性的一种相对较新的治疗方法，其侵入性低于前列腺切除术的金标准。它涉及使用直肠探针内产生的聚焦超声束对肿瘤进行凝固和消融。虽然肥胖与不利的病理特征和根治性前列腺切除术后生化复发的风险增加相关，但尚不知道高BMI对接受HIFU的男性的影响。超声探头和目标前列腺组织之间的前直肠周围脂肪组织（APFT）数量增加可能会起到屏蔽作用，反射超声波并阻止局灶性病变的完全覆盖。 Sumitomo及其同事对115位日本患者的数据进行了回顾性分析，以确定这种肥胖程度是否与HIFU后无病生存期降低有关。

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