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首页> 外文期刊>Nature reviews. Urology >Transperineal biopsy of the prostate-is this the future?
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Transperineal biopsy of the prostate-is this the future?

机译：前列腺经会阴活检-这是未来吗？

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Transperineal prostate biopsy is re-emerging after decades of being an underused alternative to transrectal biopsy guided by transrectal ultrasonography (TRUS). Factors driving this change include possible improved cancer detection rates, improved sampling of the anteroapical regions of the prostate, a reduced risk of false negative results and a reduced risk of underestimating disease volume and grade. The increasing incidence of antimicrobial resistance and patients with diabetes mellitus who are at high risk of sepsis also favours transperineal biopsy as a sterile alternative to standard TRUS-guided biopsy. Factors limiting its use include increased time, training and financial constraints as well as the need for high-grade anaesthesia. Furthermore, the necessary equipment for transperineal biopsy is not widely available. However, the expansion of transperineal biopsy has been propagated by the increase in multiparametric MRI-guided biopsies, which often use the transperineal approach. Used with MRI imaging, transperineal biopsy has led to improvements in cancer detection rates, more-accurate grading of cancer severity and reduced risk of diagnosing clinically insignificant disease. Targeted biopsy under MRI guidance can reduce the number of cores required, reducing the risk of complications from needle biopsy.
机译：经过数十年的经直肠超声检查（TRUS）指导的经直肠穿刺活检的一种未被充分利用的替代方法，经会阴前列腺活检正在重新出现。推动这一变化的因素包括可能提高的癌症检出率，改进的前列腺根尖区域的采样，降低的假阴性结果风险以及降低的低估疾病数量和等级的风险。抗菌素耐药性的增加和患有败血症高风险的糖尿病患者也赞成经会阴活检作为标准TRUS引导活检的无菌替代品。限制其使用的因素包括时间增加，培训和财务限制以及对高级麻醉的需求。此外，经会阴穿刺活检所需的设备尚未广泛获得。但是，经会阴的活检的扩大已通过多参数MRI引导的活检的增加而得以传播，而活检通常使用经会阴的方法。经会阴穿刺活检与MRI成像结合使用，可提高癌症检出率，更准确地确定癌症严重程度，并降低诊断临床上无关紧要的疾病的风险。在MRI指导下进行有针对性的活检可以减少所需的核心数目，从而减少针头活检并发症的风险。

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