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首页> 外文期刊>Nature reviews. Urology >Asymptomatic bacteriuria: When the treatment is worse than the disease
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Asymptomatic bacteriuria: When the treatment is worse than the disease

机译：无症状菌尿：当治疗比疾病差时

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摘要

Asymptomatic bacteriuria (ABU) is a condition in which bacteria are present in a noncontaminated urine sample collected from a patient without signs or symptoms related to the urinary tract. ABU must be distinguished from symptomatic UTI by the absence of signs and symptoms compatible with UTI or by clinical determination that a nonurinary etiology accounts for the patient's symptoms. Interactions between the organism, the host, and the bladder environment determine whether bacteriuria leads to ABU or to UTI. ABU is a very common condition that is often treated unnecessarily with antibioticsg - it should be detected and treated in pregnant women and patients undergoing urologic surgery, but in most other patient groups, treatment does not confer benefit and can be harmful. A change in prescribing behavior for ABU has been achieved through several fairly high-intensity interventions, such as interactive educational sessions for physicians, but whether these improvements persist beyond the study period is not known. Further research is needed to determine whether screening for and treatment of ABU is beneficial in patients with renal transplants, patients with orthotopic neobladders, patients undergoing prosthetic joint implantation, and patients with neutropenia.
机译：无症状菌尿症（ABU）是一种状况，其中细菌存在于从患者收集的未污染的尿液样本中，而没有与尿路有关的体征或症状。必须通过不存在与UTI相容的体征和症状或通过临床确定非尿病因来解释患者的症状来将ABU与有症状的UTI区别开来。生物体，宿主和膀胱环境之间的相互作用决定了细菌尿症是导致ABU还是导致UTI。 ABU是一种非常常见的疾病，通常不需要使用抗生素治疗g-应该在孕妇和接受泌尿外科手术的患者中进行检测和治疗，但是在其他大多数患者组中，治疗并不能带来益处，并且可能是有害的。通过一些相当高强度的干预措施，例如针对医生的互动式教育会议，已经实现了ABU开处方行为的改变，但是这些改善是否持续到研究期之外尚不清楚。需要进行进一步的研究以确定ABU的筛查和治疗对肾移植患者，原位新膀胱患者，人工关节植入患者和中性粒细胞减少症患者是否有益。

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