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首页> 外文期刊>Nature reviews. Urology >Effects of 10-plus-core biopsy on erectile and voiding function
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Effects of 10-plus-core biopsy on erectile and voiding function

机译：10核芯活检对勃起和排尿功能的影响

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The degree of discomfort experienced by men during prostate biopsy has been markedly decreased by the use of periprostatic nerve block (PPNB). However, the effects on erectile and voiding function-important considerations given the increasingly younger age of men undergoing biopsy-have not been intensively investigated. A prospective study performed in Germany has now evaluated the extent of these post-procedure effects in patients undergoing 10-core or 20-core prostate biopsy, with or without PPNB. The study included 198 men with suspected prostate cancer on the basis of digital rectal examination findings or elevated PSA level. Patients were randomly assigned to undergo 10-core biopsy with (n = 71) or without (n = 74) PPNB (administered as prilocaine hydrochloride). Those with a previous negative biopsy but suspiciously high PSA velocity underwent 20-core saturation biopsy with PPNB (n = 53). The primary end points were changes in the International Prostate Symptom Score (IPSS) and International Index of Erectile Function 5 (IIEF-5) score at 1, 4 and 12 weeks after biopsy. 80 patients were diagnosed with prostate cancer as a result of examination of biopsy tissue. These men were excluded from the subsequent analyses.
机译：通过使用前列腺周围神经阻滞（PPNB），男性在前列腺穿刺活检期间所经历的不适程度已显着降低。但是，由于接受活检的男性年龄越来越小，因此对勃起和排尿功能的影响是重要的考虑因素，尚未得到深入研究。现在在德国进行的一项前瞻性研究已经评估了接受或不接受PPNB的接受10芯或20芯前列腺活检的患者的这些术后影响的程度。该研究根据数字直肠检查结果或PSA水平升高，对198名疑似前列腺癌的男性进行了研究。患者被随机分配接受10针活检，有（n = 71）或无（n = 74）PPNB（盐酸丙胺卡因）。那些先前活检阴性但PSA速度可疑的患者接受了20芯PPNB饱和活检（n = 53）。主要终点是活检后1、4和12周时国际前列腺症状评分（IPSS）和国际勃起功能指数5（IIEF-5）评分的变化。通过检查活检组织，诊断出80例患有前列腺癌。这些人被排除在随后的分析之外。

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