THREE-DIMENSIONAL VISUALIZATION OF MRNA RELEASE FROM ACTIVELY TRANSCRIBING ROTAVIRUS PARTICLES

Lawton JA.; Prasad BVV.; Estes MK.

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THREE-DIMENSIONAL VISUALIZATION OF MRNA RELEASE FROM ACTIVELY TRANSCRIBING ROTAVIRUS PARTICLES

机译：主动转录轮状病毒颗粒中MRNA释放的三维可视化

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The three-dimensional structure of actively transcribing rotavirus particles reveals that the nascent mRNA transcripts generated within the core of the Virion by endogenous transcriptase complexes are translocated through the intact capsid through a system of channels at the icosahedral five-fold axes. [References: 29]

机译：主动转录轮状病毒颗粒的三维结构显示，内源转录酶复合物在病毒粒子核心内产生的新生mRNA转录物通过完整的衣壳通过二十面体五倍轴通道系统移位。 [参考：29]

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《Nature structural biology》 |1997年第2期|共4页
作者
Lawton JA.; Prasad BVV.; Estes MK.;
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正文语种 eng
中图分类生物科学;
关键词
Guanylyltransferase activity; 3-dimensional structure; Electron-microscopy; Rna-polymerase; Transcription; Virus; Reconstruction; Vp3;

机译：鸟苷酰转移酶活性;三维结构;电子显微镜;Rna聚合酶;转录;病毒;重建;Vp3;

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专利

1. THREE-DIMENSIONAL VISUALIZATION OF MRNA RELEASE FROM ACTIVELY TRANSCRIBING ROTAVIRUS PARTICLES [J] . Lawton JA., Prasad BVV., Estes MK. Nature structural biology . 1997,第2期

机译：主动转录轮状病毒颗粒中MRNA释放的三维可视化
2. Inhibition of the Inflammatory Pathway Enhances Both the in Vitro and in Vivo Transfection Activity of Exogenous in Vitro Transcribed mRNAs Delivered by Lipid Nanoparticles [J] . Ohto Takara, Konishi Manami, Tanaka Hiroki, Biological & pharmaceutical bulletin . 2019,第2期

机译：抑制炎症途径的抑制增强了通过脂质纳米粒子递送的外源性转化的体外转染活性的体外和体内转染活性
3. Modeling rotavirus-like particles production in a baculovirus expression vector system: Infection kinetics, baculovirus DNA replication, mRNA synthesis and protein production [J] . Roldao A, Vieira HL, Charpilienne A, Journal of Biotechnology . 2007,第4期

机译：在杆状病毒表达载体系统中模拟轮状病毒样颗粒的产生：感染动力学，杆状病毒DNA复制，mRNA合成和蛋白质产生
4. The Expression of Bone Matrix Protein mRNAs Around Calcium Phosphate Cement Particles Implanted into Bone [C] . Masashi Mukaida, Kunitaka Ohsawa, Masashi Neo, International Symposium on Ceramics in Medicine . 2004

机译：骨基质蛋白MRNA的表达植入骨中的磷酸钙水泥颗粒
5. Efficacy of rotavirus-like particle vaccines and pathogenesis of human rotavirus evaluated in a gnotobiotic pig model. [D] . Azevedo, Marli da Silva Pereira de. 2005

机译：轮状病毒样颗粒疫苗的功效和人类轮状病毒的发病机理已在生猪模型中进行了评估。
6. Rotavirus mRNAS are released by transcript-specific channels in the double-layered viral capsid [O] . Javier Periz, Cristina Celma, Bo Jing, 2013

机译：轮状病毒mRNAS通过双层病毒衣壳中的转录本特异性通道释放
7. Rotavirus mRNAS are released by transcript-specific channels in the double-layered viral capsid. [O] . Periz, J, Celma, C, Jing, B, 2013

机译：轮状病毒mRNAS通过双层病毒衣壳中的转录本特异性通道释放。

THREE-DIMENSIONAL VISUALIZATION OF MRNA RELEASE FROM ACTIVELY TRANSCRIBING ROTAVIRUS PARTICLES

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