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首页> 外文期刊>pediatric reports >Acceptability of “High sn-2” Infant Formula in Non-Breast Fed Healthy Term Infants Regarding Gastrointestinal Tolerability by Both Parents and Pediatrician: An Open-Label Pilot Study in the Gulf Cooperation Council (GCC) Countries
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Acceptability of “High sn-2” Infant Formula in Non-Breast Fed Healthy Term Infants Regarding Gastrointestinal Tolerability by Both Parents and Pediatrician: An Open-Label Pilot Study in the Gulf Cooperation Council (GCC) Countries

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Recent studies have highlighted the positive impact of high sn-2 formulas on gastrointestinal (GI) tolerance. We assessed the GI tolerance, acceptability, and safety of high sn-2 infant formula among non-breastfed healthy term infants in the Gulf countries. A multicenter observational study was conducted on 227 healthy-term infants who were prescribed high sn-2 palmitate infant formula and received a minimum of two formula feedings per day for the past two weeks prior to the study’s initiation. The number of stools per day decreased significantly from a median of four (interquartile range IQR = 4) at baseline to 3.0 (2) stools per day at the end of follow-up (p = 0.015). The percentage of stool amount changed significantly, where 61.2 and 33.7 of the infants had an amount of 25–50 of the diaper and 50 of the diaper, respectively (p 0.001) at the end of the follow-up. Similarly, the percentage of hard stool decreased significantly from 17.4 at baseline to 0.4 of the population at week 12 (p 0.00). The prevalence of colic and abdominal distention declined from 21.4 and 39.9 at baseline to 2.9 and 9.4 at week 12, respectively (p 0.05). The same decline was observed in abdominal distension and regurgitation score (p 0.05).

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