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首页> 外文期刊>Neurochemistry International: The International Journal for the Rapid Publication of Critical Reviews, Preliminary and Original Research Communications in Neurochemistry >Control of tangentialon-radial migration of neurons in the developing cerebral cortex.
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Control of tangentialon-radial migration of neurons in the developing cerebral cortex.

机译：控制发育中的大脑皮层神经元的切向/非径向迁移。

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摘要

Projection neurons in the developing cerebral cortex of rodents are basically born near the ventricle and migrate radially to beneath the marginal zone, whereas their cortical interneurons are generated in the ventral telencephalon and migrate tangentially to the cortex. The origins and migratory profiles of each interneuron subtype have been studied extensively in the last decade, and an enormous effort has been made to clarify the cellular and molecular mechanisms that regulate interneuron migration. More recently, the interaction between projection neurons and migrating interneurons, including how they are incorporated into their proper layers, has begun to be analyzed. In this review, I outline the most recent findings in regard to these issues and discuss the mechanisms underlying the development of cortical cytoarchitecture.
机译：啮齿类动物大脑皮层中的投射神经元基本上出生在心室附近，并径向迁移至边缘区下方，而它们的皮质中神经元在腹侧末梢神经元中生成，并切向迁移至皮质。在过去的十年中，对每种中间神经元亚型的起源和迁徙概况进行了广泛的研究，并做出了巨大的努力来阐明调节中间神经元迁移的细胞和分子机制。最近，已经开始分析投射神经元和迁移的中间神经元之间的相互作用，包括如何将它们整合到适当的层中。在这篇综述中，我概述了有关这些问题的最新发现，并讨论了皮质细胞结构发展的潜在机制。

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