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首页> 外文期刊>Neurocritical care >Prophylaxis of Venous Thrombosis in Neurocritical Care Patients: An Evidence-Based Guideline: A Statement for Healthcare Professionals from the Neurocritical Care Society
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Prophylaxis of Venous Thrombosis in Neurocritical Care Patients: An Evidence-Based Guideline: A Statement for Healthcare Professionals from the Neurocritical Care Society

机译:预防神经重症监护患者的静脉血栓形成:循证指南:神经重症监护协会医疗专业人员的声明

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摘要

The risk of death from venous thromboembolism (VTE) is high in intensive care unit patients with neurological diagnoses. This is due to an increased risk of venous stasis secondary to paralysis as well as an increased prevalence of underlying pathologies that cause endothelial activation and create an increased risk of embolus formation. In many of these diseases, there is an associated risk from bleeding because of standard VTE prophylaxis. There is a paucity of prospective studies examining different VTE prophylaxis strategies in the neurologically ill. The lack of a solid evidentiary base has posed challenges for the establishment of consistent and evidence-based clinical practice standards. In response to this need for guidance, the Neurocritical Care Society set out to develop and evidence-based guideline using GRADE to safely reduce VTE and its associated complications.
机译:有神经系统诊断的重症监护病房患者因静脉血栓栓塞(VTE)死亡的风险很高。这是由于麻痹继发的静脉淤滞的风险增加,以及引起内皮激活并导致栓子形成的风险增加的潜在病理学的增加。在许多此类疾病中,由于标准的VTE预防措施,存在相关的出血风险。缺乏针对神经病患者不同VTE预防策略的前瞻性研究。缺乏可靠的证据基础为建立一致且基于证据的临床实践标准提出了挑战。为了满足这种指导需求,神经重症监护协会着手开发使用GRADE的循证指南,以安全地减少VTE及其相关并发症。

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