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Pick's pathology in Parkinson's disease with dementia

机译:皮克氏病在帕金森氏病与痴呆症中的病理

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摘要

In Parkinson's disease (PD) dementia occurs in up to 40% of patients. Its neuropathological substrate is still controversial. We report clinical and neuropathological findings in a patient with PD who developed dementia during the course of the disease. We show that in PD, Pick's pathology may also contribute to cognitive decline.The patient was a 62-year-old woman presenting with right hand resting tremor, with good levodopa response. Two years later, she suffered from depressive symptoms and episodes of disorientation.
机译:在帕金森氏病(PD)中,痴呆症的发生率高达40%。其神经病理学底物仍存在争议。我们报告在疾病过程中发生痴呆的PD患者的临床和神经病理学发现。我们发现在PD中,Pick的病理学也可能导致认知功能下降。该患者是一名62岁的女性,右手休息震颤,左旋多巴反应良好。两年后,她患有抑郁症状和迷失感发作。

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