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Clinical relevance of action observation in upper-limb stroke rehabilitation: A possible role in recovery of functional dexterity. A randomized clinical trial

机译:上肢卒中康复中行动观察的临床意义:在功能敏捷恢复中的可能作用。一项随机临床试验

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Objective. A randomized controlled observer-blind trial was designed to evaluate the effectiveness of action observation as an add-on treatment to the standard rehabilitation of upper-limb function, early after stroke. Methods. Stroke survivors (N = 102) were consecutively recruited from 13 centers 30 days (±7) after a first-ever stroke and randomly assigned to the experimental (EG) or control group (CG). EG participants watched video footage of daily routine tasks (actions) carried out with the upper limb in order to prepare to imitate the presented action. At the end of each sequence, a therapist prompted the patient to perform the same movement for 2 minutes, providing help when needed. Static images without animals or human beings were shown to the CG. At the end of each sequence, the CG executed movements that simulated the shoulder and elbow joint mobilization activities performed by the EG. Results for the Fugl-Meyer test, Frenchay Arm test, Box and Block test (BBT), Modified Ashworth Scale, and Functional Independence Measure Motor items were recorded before treatment (T0), after 4 weeks of treatment (T1), and at the follow-up visit 4 to 5 months after the conclusion of treatment (T2). Results. An improvement over time was appreciated on all measures of impairment and functional ability with both treatment programs. A Time × Treatment interaction emerged from the generalized estimating equations analysis of BBT, showing significant T0-T1 and T0-T2 differences in favor of EG. Conclusion. This multicenter trial endorses the use of action observation in upper-extremity rehabilitation, along with a role for the mirror neuron system in poststroke recovery.
机译:目的。设计了一项随机对照的观察者盲试验,以评估动作观察作为中风后早期上肢功能标准康复的附加治疗的有效性。方法。首次卒中后30天(±7),从13个中心连续招募卒中幸存者(N = 102),并将其随机分配至实验组(EG)或对照组(CG)。 EG参与者观看了上肢执行的日常例行任务(动作)的录像,以准备模仿所呈现的动作。在每个序列的结尾,治疗师会提示患者进行相同的运动2分钟,并在需要时提供帮助。没有动物或人类的静态图像显示给CG。在每个序列的末尾,CG执行模拟EG进行的肩膀和肘关节动员活动的动作。 Fugl-Meyer检验,Frenchay Arm检验,Box和Block检验(BBT),改良Ashworth量表和功能独立性测量的结果在治疗前(T0),治疗4周后(T1)和运动前记录。治疗结束后4至5个月进行随访(T2)。结果。两种治疗方案的所有损伤和功能能力指标均随着时间的推移得到了改善。 BBT的广义估计方程分析出现了时间×治疗相互作用,显示出T0-T1和T0-T2的显着差异,有利于EG。结论。这项多中心试验支持在上肢康复中使用动作观察,以及镜像神经元系统在中风后恢复中的作用。

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