Dystroglycan: important player in skeletal muscle and beyond.

Cohn RD

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Dystroglycan: important player in skeletal muscle and beyond.

机译：dystroglycan：骨骼肌及其他部位的重要角色。

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Dystroglycan is a transmembrane protein that connects the extracellular matrix to the cytoskeleton. Given the ubiquitous tissue expression of dystroglycan, different functional roles in various organ systems have been characterized during the past decade. More recently, aberrant glycosylation of dystroglycan has been identified as a novel pathogenetic mechanism in several forms of congenital and late onset muscular dystrophy syndromes. The current review summarizes the recent scientific achievements as they relate to the function of dystroglycan under normal and pathophysiological conditions.

机译：dystroglycan是一种跨膜蛋白，可将细胞外基质与细胞骨架相连。考虑到dystroglycan普遍存在的组织表达，在过去的十年中已表征了在各种器官系统中的不同功能。最近，肌营养不良糖基糖基化异常已被鉴定为多种形式的先天性和迟发性肌营养不良综合症的新型致病机制。本综述总结了最近的科学成就，因为它们与正常和病理生理条件下的dystroglycan的功能有关。

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《Neuromuscular disorders: NMD》 |2005年第3期|共11页
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Cohn RD;
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正文语种 eng
中图分类神经病学与精神病学;
关键词
Dystroglycans; Muscle; Skeletal; 肌; 骨骼;

机译：Dystroglycans;Muscle;Skeletal;肌;骨骼;

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1. Dystroglycan: important player in skeletal muscle and beyond. [J] . Cohn RD Neuromuscular disorders: NMD . 2005,第3期

机译：dystroglycan：骨骼肌及其他部位的重要角色。
2. An intricate balance of muscle damage and protein synthesis: the key players in skeletal muscle hypertrophy following resistance training [J] . Keefe Giselle, Wright Craig The Journal of Physiology . 2016,第24期

机译：肌肉损伤和蛋白质合成的复杂平衡：抗性训练后骨骼肌肥大的关键球员
3. An intricate balance of muscle damage and protein synthesis: the key players in skeletal muscle hypertrophy following resistance training [J] . Keefe Giselle, Wright Craig The Journal of Physiology . 2016,第24期

机译：肌肉损伤和蛋白质合成之间的复杂平衡：抵抗训练后骨骼肌肥大的关键因素
4. Comparative proteomic profiling of purified dystroglycan protein complexes in wild type and dystrophic murine muscle [C] . Jung H Yoon, Eric Johnson, Laura T. Martin, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2012

机译：纯化试蛋白蛋白复合物在野生型和营养不良鼠肌肉中的比较蛋白质组学分析
5. Effects of lower- and higher- volume resistance exercise on serum testosterone and skeletal muscle androgen receptor content in men: Subsequent effects on the mrna expression of insulin-like growth factor peptide and myostatin in skeletal muscle. [D] . Spillane, Mike. 2013

机译：较低和较高容量的抵抗运动对男性血清睾丸激素和骨骼肌雄激素受体含量的影响：随后对骨骼肌中胰岛素样生长因子肽和肌生成抑制素的mRNA表达的影响。
6. An intricate balance of muscle damage and protein synthesis: the key players in skeletal muscle hypertrophy following resistance training [O] . Giselle Keefe, Craig Wright 2016

机译：肌肉损伤与蛋白质合成之间的复杂平衡：抵抗训练后骨骼肌肥大的关键因素
7. Disruption of Dag1 in Differentiated Skeletal Muscle Reveals a Role for Dystroglycan in Muscle Regeneration [O] . Cohn Ronald D., Henry Michael D., Michele Daniel E., 2002

机译：Dag1在分化的骨骼肌中的破坏揭示肌营养不良蛋白在肌肉再生中的作用。

Dystroglycan: important player in skeletal muscle and beyond.

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