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首页> 外文期刊>Neuron >Complexins living up to their name--new light on their role in exocytosis.
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Complexins living up to their name--new light on their role in exocytosis.

机译:Complexins不辜负他们的名字-它们在胞吐作用中的作用有了新发现。

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摘要

Ca(2+)-dependent exocytosis of synaptic vesicles is mediated by the SNARE proteins synaptobrevin/VAMP, SNAP-25, and syntaxin. SNARE function is controlled by conserved regulatory proteins, including the complexins. In a study by Xue et al. in this issue of Neuron, contradictory data from Drosophila and mouse complexin mutants have been resolved, revealing a complex pattern of facilitatory and inhibitory domains.
机译:钙(2+)依赖的突触小泡胞吐作用由SNARE蛋白质synaptobrevin / VAMP,SNAP-25和Syntaxin介导。 SNARE功能由保守的调节蛋白(包括复合蛋白)控制。在薛等人的研究中。在本期Neuron中,果蝇和小鼠complexin突变体的矛盾数据已得到解决,揭示了促进域和抑制域的复杂模式。

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