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首页> 外文期刊>Neuropathology: official journal of the Japanese Society of Neuropathology >Dedifferentiated chordoid meningioma with rhabdomyosarcomatous differentiation on the middle cranial fossa
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Dedifferentiated chordoid meningioma with rhabdomyosarcomatous differentiation on the middle cranial fossa

机译：颅中窝颅内横纹肌肉瘤样分化的去分化脉络膜脑膜瘤

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摘要

A 46-year-old woman presented with headache and right hemiparesis. MRI demonstrated a mass in the left middle fossa. Total resection was performed. A histological examination of the tumor specimen showed several characteristic morphological features. A chordoid meningioma showing an epithelial-like palisade arrangement was observed. An anaplastic short spindle cell tumor exhibiting a fascicular pattern was considered to be a rhabdomyosarcoma. After conventional radiotherapy, the tumor was well controlled without any neurological deficit for 20 months. When subsequent recurrences were observed, the patient was treated by surgery, stereotactic radiosurgery and chemotherapy. Thirty-two months after the initial treatment, the patient died due to intracranial dissemination and an autopsy was performed. The histological examination of the recurrent and autopsy specimens showed a prominent sarcoma component. This case appears to be the first reported intracranial tumor diagnosed as a dedifferentiated chordoid meningioma with rhabdomyosarcomatous differentiation.
机译：一名46岁的妇女出现头痛和右偏瘫。 MRI显示左中窝有肿块。进行全切除。肿瘤标本的组织学检查显示了几个特征形态特征。观察到呈上皮样栅状排列的脉络膜脑膜瘤。表现为束状模式的间变性短梭状细胞瘤被认为是横纹肌肉瘤。经过常规放疗后，肿瘤在20个月内得到了良好的控制，没有任何神经系统缺陷。当观察到随后的复发时，通过手术，立体定向放射外科手术和化学疗法治疗该患者。初始治疗后的32个月，该患者因颅内扩散而死亡，并进行了尸检。复发和尸检标本的组织学检查显示肉瘤成分突出。该病例似乎是首次报道的颅内肿瘤，被诊断为伴横纹肌肉瘤分化的去分化脉络膜脑膜瘤。

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