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首页> 外文期刊>Neuron >Motion processing streams in Drosophila are behaviorally specialized.
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Motion processing streams in Drosophila are behaviorally specialized.

机译:果蝇中的运动处理流是行为专用的。

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摘要

Motion vision is an ancient faculty, critical to many animals in a range of ethological contexts, the underlying algorithms of which provide central insights into neural computation. However, how motion cues guide behavior is poorly understood, as the neural circuits that implement these computations are largely unknown in any organism. We develop a systematic, forward genetic approach using high-throughput, quantitative behavioral analyses to identify the neural substrates of motion vision in Drosophila in an unbiased fashion. We then delimit the behavioral contributions of both known and novel circuit elements. Contrary to expectation from previous studies, we find that orienting responses to motion are shaped by at least two neural pathways. These pathways are sensitive to different visual features, diverge immediately postsynaptic to photoreceptors, and are coupled to distinct behavioral outputs. Thus, behavioral responses to complex stimuli can rely on surprising neural specialization from even the earliest sensory processing stages.
机译:运动视觉是一门古老的方法,对许多动物而言,在各种伦理学背景下都是至关重要的,其基础算法为神经计算提供了中心见识。但是,对于运动线索如何指导行为知之甚少,因为实现这些计算的神经回路在任何生物体中都是未知的。我们开发了一种系统的,前瞻性的遗传方法,使用高通量,定量的行为分析来以无偏见的方式识别果蝇中运动视觉的神经基质。然后,我们界定了已知和新颖电路元件的行为贡献。与先前研究的预期相反,我们发现定向运动响应至少受两个神经通路的影响。这些途径对不同的视觉特征敏感,突触后立即与感光细胞分开,并与不同的行为输出耦合。因此,对复杂刺激的行为反应甚至可以依靠来自最早的感觉处理阶段的令人惊讶的神经专长。

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