We read with grcal interest the article by Takiyama et al. describing a case of CNS lymphomatoid granulomatosis (LYG). The authors indicated that the infiltrating cells in the brain consisted of small lymphocytes without overt nuclear atypism in the perivascular areas, and that the lymphocytes were mainly CD3-positive, and rarely CD20-positive. We considered that the clinical and radiological findings in this case were consistent with LYG. On the other hand, in this report, information regarding the Hpstein-Barr virus (EBV) infection was not described.
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