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首页> 外文期刊>Neuron >Electrical coupling and neuronal synchronization in the Mammalian brain.
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Electrical coupling and neuronal synchronization in the Mammalian brain.

机译:哺乳动物大脑中的电耦合和神经元同步。

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摘要

Certain neurons in the mammalian brain have long been known to be joined by gap junctions, which are the most common type of electrical synapse. More recently, cloning of neuron-specific connexins, increased capability of visualizing cells within brain tissue, labeling of cell types by transgenic methods, and generation of connexin knockouts have spurred a rapid increase in our knowledge of the role of gap junctions in neural activity. This article reviews the many subtleties of transmission mediated by gap junctions and the mechanisms whereby these junctions contribute to synchronous firing.
机译:长期以来,哺乳动物脑中的某些神经元已被称为间隙连接,这是最常见的电突触类型。最近,神经元特异性连接蛋白的克隆,脑组织内细胞可视化能力的增强,通过转基因方法标记细胞类型以及连接蛋白敲除的产生,促使我们迅速了解了间隙连接在神经活动中的作用。本文回顾了由间隙连接介导的传输的许多微妙之处以及这些连接促成同步点火的机制。

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