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首页> 外文期刊>Neuron >Modulation of inferotemporal cortex activation during verbal working memory maintenance.
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Modulation of inferotemporal cortex activation during verbal working memory maintenance.

机译：口头工作记忆维持过程中颞下皮质激活的调节。

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摘要

Regions of the left inferotemporal cortex are involved in visual word recognition and semantics. We utilized functional magnetic resonance imaging to localize an inferotemporal language area and to demonstrate that this area is involved in the active maintenance of visually presented words in working memory. Maintenance activity in this inferotemporal area showed an effect of memory load for words, but not pseudowords. In the absence of visual input, the selective modulation of this language-related inferotemporal area for the maintenance of words is accompanied by an increased functional connectivity with left prefrontal cortex. These results demonstrate an involvement of inferotemporal cortex in verbal working memory and provide neurophysiological support for the notion that nonphonological language representations can be recruited in the service of verbal working memory. More generally, they suggest that verbal working memory should be conceptualized as the frontally guided, sustained activation of pre-existing cortical language representations.
机译：左颞下皮层的区域参与视觉单词的识别和语义。我们利用功能磁共振成像来定位颞下语言区域，并证明该区域参与了工作记忆中视觉呈现单词的主动维护。在这个下颞区域的维护活动显示了单词而不是伪单词的记忆负荷的影响。在没有视觉输入的情况下，该语言相关的颞下区域的选择性调节（用于维持单词）与左前额叶皮层的功能连接性增加。这些结果表明颞下皮质参与言语工作记忆，并为非言语语言表示可以为言语工作记忆服务而募集的观念提供了神经生理学支持。他们更普遍地认为，言语工作记忆应被概念化为先前存在的皮层语言表征的前导性，持续性激活。

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