...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Neuron >Single-photon absorptions evoke synaptic depression in the retina to extend the operational range of rod vision.
【24h】

Single-photon absorptions evoke synaptic depression in the retina to extend the operational range of rod vision.

机译：单光子吸收引起视网膜中的突触抑制，以扩大视杆的操作范围。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Adaptation or gain control allows sensory neurons to encode diverse stimuli using a limited range of output signals. Rod vision exemplifies a general challenge facing adaptational mechanisms-balancing the benefits of averaging to create a reliable signal for adaptation with the need to adapt rapidly and locally. The synapse between rod bipolar and AII amacrine cells dominates adaptation at low light levels. We find that adaptation occurs independently at each synapse and completes in <500 ms. This limited spatial and temporal integration suggests that the absorption of a single photon modulates gain. Indeed, responses to pairs of brief dim flashes showed directly that synaptic gain was depressed for 100-200 ms following transmission of a single-photon response. Presynaptic mechanisms mediated this synaptic depression. Thus, the division of light into discrete photons controls adaptation at this synapse, and gain varies with the irreducible statistical fluctuations in photon arrival.
机译：适应或增益控制允许感觉神经元使用有限范围的输出信号来编码各种刺激。 Rod视觉例证了适应机制面临的一般挑战，即在求平均值以创建可靠的适应信号的需求与快速和局部适应的需求之间取得平衡。杆双极和AII无长突细胞之间的突触在弱光条件下占主导地位。我们发现适应在每个突触处独立发生，并在<500毫秒内完成。这种有限的时空积分表明，单个光子的吸收会调节增益。实际上，对短时暗光对的响应直接表明，在传输单光子响应后，突触增益持续了100-200 ms。突触前机制介导这种突触抑制。因此，将光分成离散的光子将控制此突触的适应性，并且增益随光子到达中不可减少的统计波动而变化。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号