Less means more: inhibition of spontaneous firing triggers persistent increases in excitability.

Hausser M; Monsivais P

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Less means more: inhibition of spontaneous firing triggers persistent increases in excitability.

机译：更少意味着更多：自发放电的抑制触发兴奋性的持续增加。

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Modulation of intrinsic excitability is an alternative to classical synaptic plasticity for implementing activity-dependent changes in neuronal networks. In this issue of Neuron, Nelson et al. reveal a new form of plasticity of intrinsic excitability that can be triggered rapidly when synaptic inhibition reduces spontaneous firing, resulting in persistent enhancement of firing rate and neuronal gain.

机译：内在兴奋性的调制是经典的突触可塑性的替代方案，用于在神经元网络中实现活动依赖的变化。在本期《神经元》中，尼尔森（Nelson）等人。揭示了一种新形式的内在兴奋性可塑性，当突触抑制降低自发放电时，可以迅速触发，从而持续提高放电速率和神经元增益。

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《Neuron》 |2003年第3期|共3页
作者
Hausser M; Monsivais P;
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原文格式 PDF
正文语种 eng
中图分类基础医学;
关键词
Psychological inhibition; plasticity; Neurons; 神经元;

机译：Psychological inhibition;plasticity;Neurons;神经元;

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1. Less means more: inhibition of spontaneous firing triggers persistent increases in excitability. [J] . Hausser M, Monsivais P Neuron . 2003,第3期

机译：更少意味着更多：自发放电的抑制触发兴奋性的持续增加。
2. Persistent changes in spontaneous firing of Purkinje neurons triggered by the nitric oxide signaling cascade. [J] . Smith SL, Otis TS The Journal of Neuroscience: The Official Journal of the Society for Neuroscience . 2003,第2期

机译：一氧化氮信号级联触发的浦肯野神经元自发放电的持续变化。
3. Increased firing frequency of spontaneous action potentials in cerebellar Purkinje neurons of db/db mice results from altered auto-rhythmicity and diminished GABAergic tonic inhibition [J] . Maria E. Forero-Vivas, Arturo Hernández-Cruz General Physiology and Biophysics . 2014,第1期

机译：db / db小鼠小脑浦肯野神经元自发动作电位的激发频率增加是由于自律性改变和GABA能补剂抑制作用减弱
4. On the firing variability of the integrate-and-fire neurons with partial reset in the presence of inhibition [C] . Chris Christodoulou Computational neuroscience meeting . 2002

机译：在抑制存在下部分复位的射击变异性
5. The GABAA receptor is a critical part of the sensing machinery that triggers homeostatic plasticity of synaptic strength and intrinsic excitability. [D] . Wilhelm, Jennifer Caldwell. 2008

机译：GABAA受体是传感机制的关键部分，可触发突触强度和内在兴奋性的稳态可塑性。
6. Persistent Changes in Spontaneous Firing of Purkinje Neurons Triggered by the Nitric Oxide Signaling Cascade [O] . Spencer L. Smith, Thomas S. Otis 2003

机译：一氧化氮信号级联触发的浦肯野神经元自发放电的持续变化
7. Less Means More Inhibition of Spontaneous Firing Triggers Persistent Increases in Excitability [O] . Häusser Michael, Monsivais Pablo 2003

机译：更少意味着更多地抑制自发触发，持续增加兴奋性

Less means more: inhibition of spontaneous firing triggers persistent increases in excitability.

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