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首页> 外文期刊>Neuron >Close encounters: how cortical neurons find and connect to their correct synaptic partners depends on the cell type.
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Close encounters: how cortical neurons find and connect to their correct synaptic partners depends on the cell type.

机译:亲密接触:皮质神经元如何找到并连接到其正确的突触伴侣取决于细胞类型。

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In this issue of Neuron, Stepanyants et al. embark on quantitative analyses of the axonal and dendritic arbors of cortical neurons. They test whether the paths taken by axons actually bring them closer to their true synaptic partners than they would have gotten by chance encounters based on the same axon trajectories. The results depend on the type of presynaptic neuron. Inhibitory cells take paths that explicitly link them to their actual partners while excitatory axons are as likely to have close encounters with actual partners as with other neurons. These results suggest that the mechanisms for selectivity depend on the type of presynaptic neuron.
机译:在本期《神经元》中,Stepanyants等人。着手对皮质神经元的轴突和树突状树突进行定量分析。他们测试了轴突所采取的路径是否实际上使他们更接近其真正的突触伴侣,而不是他们基于相同的轴突轨迹偶然相遇。结果取决于突触前神经元的类型。抑制性细胞的路径明确地将其链接到其实际伴侣,而兴奋性轴突与其他神经元一样,与实际伴侣的接触也很可能。这些结果表明选择性的机制取决于突触前神经元的类型。

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