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Relative contribution of feedforward excitatory connections to expression of ocular dominance plasticity in layer 4 of visual cortex.

机译:前馈兴奋性连接对视觉皮质第4层中眼优势塑性表达的相对贡献。

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摘要

Brief monocular deprivation (MD) shifts ocular dominance (OD) in primary visual cortex by causing depression of responses to the deprived eye. Here we address the extent to which the shift is expressed by a modification of excitatory synaptic transmission. An OD shift was first induced with 3 days of MD, and then the influences of intracortical polysynaptic inhibitory and excitatory synapses were pharmacologically removed, leaving only "feedforward" thalamocortical synaptic currents. The results show that the rapid OD shift following MD is strongly expressed at the level of thalamocortical synaptic transmission.
机译:短暂的单眼剥夺(MD)通过引起对被剥夺的眼睛的反应降低来改变初级视觉皮层的眼部优势(OD)。在这里,我们讨论了通过兴奋性突触传递的修改表达移位的程度。首先用3天的MD诱导OD改变,然后用药理学方法消除皮质内多突触抑制和兴奋性突触的影响,仅留下“前馈”丘脑皮层突触电流。结果表明,在丘脑皮层突触传递水平强烈表达了MD后的快速OD移动。

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