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首页> 外文期刊>Neuron >Behavioral and neural analysis of extinction.
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Behavioral and neural analysis of extinction.

机译：灭绝的行为和神经分析。

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The neural mechanisms by which fear is inhibited are poorly understood at the present time. Behaviorally, a conditioned fear response may be reduced in intensity through a number of means. Among the simplest of these is extinction, a form of learning characterized by a decrease in the amplitude and frequency of a conditioned response when the conditioned stimulus that elicits it is repeatedly nonreinforced. Because clinical interventions for patients suffering from fear dysregulation seek to inhibit abnormal, presumably learned fear responses, an understanding of fear extinction is likely to inform and increase the efficacy of these forms of treatment. This review considers the behavioral, cellular, and molecular literatures on extinction and presents the most recent advances in our understanding while identifying issues that require considerable further research.
机译：目前，对恐惧被抑制的神经机制知之甚少。从行为上讲，可以通过多种手段来降低条件恐惧反应的强度。其中最简单的一种是灭绝，这是一种学习形式，其特征是当反复激发未激发的条件刺激时，条件响应的幅度和频率会降低。因为针对患有恐惧失调的患者的临床干预旨在抑制异常的，大概是学到的恐惧反应，所以对恐惧消灭的了解可能会告知并增加这些治疗形式的疗效。这篇综述考虑了有关灭绝的行为，细胞和分子方面的文献，并提出了我们了解的最新进展，同时确定了需要进一步研究的问题。

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