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首页> 外文期刊>Neuron >Presynaptic depolarization rate controls transmission at an invertebrate synapse.
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Presynaptic depolarization rate controls transmission at an invertebrate synapse.

机译：突触前的去极化率控制着无脊椎动物突触的传递。

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摘要

Second-order neurons L1-3 of the locust ocellar pathway make inhibitory synapses with each other. Although the synapses transmit graded potentials, transmission depresses rapidly and completely so that a synapse only transmits when the presynaptic terminal depolarizes rapidly. The rate at which a presynaptic neuron depolarizes determines the rate at which a postsynaptic neuron hyperpolarizes, and neurotransmitter is only released during a fixed 2 ms long period. Consequently, the amplitude of a postsynaptic potential depends on the rate rather than the amplitude of a presynaptic depolarization. Following a postsynaptic potential, a synapse recovers from depression over about a second. The synapse recovers from depression even if the presynaptic terminal is held depolarized.
机译：刺槐卵母细胞途径的二级神经元L1-3相互抑制突触。尽管突触传递分级的电位，但传递却迅速而完全地降低，因此，突触仅在突触前末端快速去极化时才传递。突触前神经元去极化的速率决定了突触后神经元超极化的速率，并且神经递质仅在固定的2 ms长周期内释放。因此，突触后电位的幅度取决于速率而不是突触前去极化的幅度。突触后电位后，突触在大约一秒钟内从抑郁中恢复。即使突触前末端保持去极化状态，突触也可从抑郁中恢复。

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