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Origin and classification of neocortical interneurons.

机译:新皮层神经元的起源和分类。

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Neocortical interneurons are very diverse in morphological, physiological, molecular, and developmental characteristics. Recent work is discovering strong correlations between these phenotypic features, confirming the intuition of Cajal and Lorente that distinct classes of interneurons exist, each presumably mediating a different circuit function. A paper by Butt et al. in this issue of Neuron describes correlations between the developmental origin of interneurons and their anatomical, electrophysiological, and molecular properties. An effort to standardize the nomenclature of interneurons is underway. Because different interneuron subtypes have different ontogenic origin, they could be classified based on their developmental specification by transcription factors.
机译:新皮质中间神经元在形态,生理,分子和发育特征上非常多样化。最近的工作正在发现这些表型特征之间的强相关性,证实了Cajal和Lorente的直觉,即存在不同类型的中间神经元,每个中间元可能介导不同的电路功能。 Butt等人的论文。在Neuron的这一期中,他描述了中间神经元的发育起源与其解剖学,电生理学和分子特性之间的相关性。正在努力标准化中间神经元的命名法。由于不同的中间神经元亚型具有不同的个体起源,因此可以根据它们的发育规格通过转录因子对其进行分类。

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