During pauses in exploration, ensembles of place cells in the rat hippocampus re-express firing sequences corresponding to recent spatial experience. Such replay high-frequency (approximately 200 Hz) oscillations that are associated with increased hippocampal-cortical communication. In previous studies, rats exploring small environments showed replay anchored to the rat's current location and compressed in time into a single ripple event. Here, we show, using a neural decoding approach, that firing sequences corresponding to long runs through a large environment are replayed with high fidelity and that such replay can begin at remote locations on the track. Extended replay proceeds at a characteristic virtual speed of approximately 8 m/s and remains coherent across trains of ripple events. These results suggest that extended replay is composed of chains of shorter subsequences, which may reflect a strategy for the storage and flexible expression of memories of prolonged experience.
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机译：在探索中的停顿期间，大鼠海马中的位置细胞群重新表达了与最近的空间经验相对应的发射序列。这种重放高频（约200 Hz）的振荡与海马-皮质通讯的增加有关。在先前的研究中，探索小型环境的老鼠表现出重播锚定在老鼠的当前位置，并被及时压缩成单个波纹事件。在这里，我们展示了使用神经解码方法，可以以高保真度重播对应于穿越大环境的长距离的射击序列，并且此类重播可以在轨道的较远位置开始。扩展的重放以大约8 m / s的典型虚拟速度进行，并且在一系列波纹事件之间保持一致。这些结果表明，延长的重放由较短的子序列链组成，这可能反映了长期经验记忆的存储和灵活表达策略。
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