Cholinergic signaling through synaptic SK channels: it's a protein kinase but which one?

Maylie J; Adelman JP

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Cholinergic signaling through synaptic SK channels: it's a protein kinase but which one?

机译：通过突触SK通道的胆碱能信号传导：它是一种蛋白激酶，但是哪个？

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Cholinergic signaling modulates synaptic responses and influences cognition. In this issue of Neuron, two groups (Buchanan et al. and Giessel and Sabatini) present evidence that cholinergic signaling enhances postsynaptic responses in CA1 neurons by decreasing synaptic SK channel activity. However, they come to different conclusions about the protein kinases involved in this process.

机译：胆碱能信号传导调节突触反应并影响认知。在本期《神经元》中，两组（Buchanan等人以及Giessel和Sabatini）提供了证据，表明胆碱能信号传导通过降低突触SK通道活性来增强CA1神经元的突触后反应。但是，他们对此过程中涉及的蛋白激酶有不同的结论。

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《Neuron》 |2010年第5期|共3页
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Maylie J; Adelman JP;
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1. Cholinergic signaling through synaptic SK channels: it's a protein kinase but which one? [J] . Maylie J, Adelman JP Neuron . 2010,第5期

机译：通过突触SK通道的胆碱能信号传导：它是一种蛋白激酶，但是哪个？
2. Local synaptic integration of mitogen-activated protein kinase and protein kinase A signaling mediates intermediate-term synaptic facilitation in Aplysia [J] . Xiaojing Ye, Andreea Marina, Thomas J. Carew Proceedings of the National Academy of Sciences of the United States of America . 2012,第44期

机译：丝裂原活化的蛋白激酶和蛋白激酶A信号的局部突触整合介导海藻的中期突触促进。
3. Convergent Metabotropic Signaling Pathways Inhibit SK Channels to Promote Synaptic Plasticity in the Hippocampus [J] . Tigaret Cezar M., Chamberlain Sophie E. L., Sadowski Joseph H. L. P., The Journal of Neuroscience: The Official Journal of the Society for Neuroscience . 2018,第43期

机译：收敛代谢信号通路抑制SK频道，以促进海马中的突触可塑性
4. Tauroursodeoxycholic acid antagonizes taurolithocholic acid-induced cholestasis via a cooperative protein kinase C- and protein kinase A-dependent signalling pathway in the perfused rat liver [C] . R. WIMWIER, S. HOHENESTER, T. PUSL, International Bile Acid Meeting . 2007

机译：TauroSodoxcholic酸通过在灌注的大鼠肝脏中通过合作蛋白激酶C-和蛋白激酶A依赖的信号传导途径拮抗柚子胆酸诱导的胆汁淤积
5. S100A1 competes with calmodulin for calmodulin binding proteins, CaV1.2 and SK2 channels. [D] . Metzler-Wilson, Kristen. 2010

机译：S100A1与钙调蛋白竞争钙调蛋白结合蛋白，CaV1.2和SK2通道。
6. Cholinergic Signaling through Synaptic SK Channels: It’s aProtein Kinase but Which One? [O] . James Maylie, John P. Adelman -1

机译：胆碱能信号通过突触sK通道：这是一个蛋白激酶但哪一个？
7. Cholinergic Signaling through Synaptic SK Channels: It's a Protein Kinase but Which One? [O] . Maylie James, Adelman John P. 2010

机译：通过突触SK通道的胆碱能信号传导：这是一种蛋白激酶，但哪一个呢？
8. Macromolecular Instabilities and Dynamical Coding in Brain Enzymes, Polypeptide Ligands, Polypeptide and Cholinergic Receptors, and Sodium and Cholinergic Channel Proteins [R] . Mandell, A. J. 1988

机译：脑酶，多肽配体，多肽和胆碱能受体以及钠和胆碱能通道蛋白的大分子不稳定性和动态编码

Cholinergic signaling through synaptic SK channels: it's a protein kinase but which one?

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