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首页> 外文期刊>Neuron >Microstructure of temporo-parietal white matter as a basis for reading ability: evidence from diffusion tensor magnetic resonance imaging (see comments)
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Microstructure of temporo-parietal white matter as a basis for reading ability: evidence from diffusion tensor magnetic resonance imaging (see comments)

机译：颞顶白质的微观结构作为阅读能力的基础：弥散张量磁共振成像的证据（见评论）

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摘要

Diffusion tensor magnetic resonance imaging (MRI) was used to study the microstructural integrity of white matter in adults with poor or normal reading ability. Subjects with reading difficulty exhibited decreased diffusion anisotropy bilaterally in temporoparietal white matter. Axons in these regions were predominantly anterior-posterior in direction. No differences in T1-weighted MRI signal were found between poor readers and control subjects, demonstrating specificity of the group difference to the microstructural characteristics measured by diffusion tensor imaging (DTI). White matter diffusion anisotropy in the temporo-parietal region of the left hemisphere was significantly correlated with reading scores within the reading-impaired adults and within the control group. The anisotropy reflects microstructure of white matter tracts, which may contribute to reading ability by determining the strength of communication between cortical areas involved in visual, auditory, and language processing.
机译：扩散张量磁共振成像（MRI）用于研究阅读能力差或正常的成年人白质的微结构完整性。有阅读困难的受试者双侧颞顶白质的弥散各向异性降低。这些区域中的轴突主要是前后方向。在差的阅读者和对照对象之间未发现T1加权MRI信号的差异，这说明了群体差异对通过弥散张量成像（DTI）测量的微结构特征的特异性。左半球颞顶区的白质扩散各向异性与阅读障碍成年人和对照组的阅读分数显着相关。各向异性反映了白质束的微观结构，可以通过确定涉及视觉，听觉和语言处理的皮质区域之间的交流强度来提高阅读能力。

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