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The economics of personalized medicine: Commercialization as a driver of return on investment

机译:个性化医学的经济学:商业化是投资回报的驱动力

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Optimizing commercialization of drugs is the sine qua non of the pharmaceutical industry and intensive work has been done to characterize fully the drivers of drug adoption and understand the resources required to optimize those drivers for full adoption of drugs. Conversely, while the pharmaceutical industry is actively embracing the new personalized medicine (PM) paradigm, much work remains to be done to understand fully what drives adoption of targeted therapies and how to resource those drivers appropriately. While the industry is slowly learning from its early missteps, progress is still inhibited by a lack of understanding of the specific hurdles that individual development teams face in developing and commercializing targeted therapies and the requirement for budgets specifically aimed at driving test adoption. This article considers the benefits of optimizing commercial planning in the PM space and the potential negative impact in potentially failing to optimize that planning. Real world insights are used to illustrate that a far broader commercial lens is required in the PM space and will touch on functional areas not usually included in the context of 'commercial' decisions.
机译:优化药物的商业化是制药业的先决条件,并且已经进行了大量工作来充分表征药物采用的驱动因素,并了解优化这些驱动因素以充分采用药物所需的资源。相反,在制药行业积极采用新的个性化医学(PM)范式的同时,要充分理解推动目标疗法的采用以及如何适当地利用这些驱动因素,还有许多工作要做。尽管该行业正在从早期的失误中缓慢学习,但是由于缺乏对各个开发团队在开发和商业化目标疗法方面面临的具体障碍以及对专门用于推动测试采用的预算要求的了解,仍然阻碍了进步。本文考虑了在PM空间中优化商业计划的好处,以及可能无法优化该计划的潜在负面影响。现实世界的见解被用来说明在PM空间中需要一个更广泛的商业镜头,并将涉及通常不在“商业”决策范围内的功能区域。

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