...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Neurobiology of Aging: Experimental and Clinical Research >Healthy aging is associated with increased neural processing of positive valence but attenuated processing of emotional arousal: An fMRI study
【24h】

Healthy aging is associated with increased neural processing of positive valence but attenuated processing of emotional arousal: An fMRI study

机译：功能性MRI研究表明，健康的衰老与正价神经处理能力的增强有关，而情绪唤醒的处理能力却减弱了

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Arousal and valence play key roles in emotional perception, with normal aging leading to changes in the neural substrates supporting valence processing. The objective of this study was to investigate normal age-related changes in the neural substrates of emotional arousal processing. Twenty-three young and 23 older, healthy women underwent functional magnetic resonance imaging as they viewed images which were neutral or positive in valence and which varied in arousal level from low to high. Using a parametric modulation approach, we examined how the blood oxygen-level dependent signal varied with single trial subjective ratings of valence and arousal, and whether this differed with age. In accordance with previous studies we found that the older group showed greater activation in response to positive valence, in the left amygdala, left middle temporal gyrus and right lingual gyrus. In contrast however, they showed reduced reactivity to emotional arousal, in occipital and temporal visual cortices bilaterally, the left inferior parietal cortex, and the supplementary motor area bilaterally. This study represents the first of its kind to clearly dissociate how aging affects the neural correlates of emotional arousal and valence. The changes in arousal processing may in part be mediated by the functional reorganization evident in the aging brain, such as reduced activation of the posterior cortices as described by the posterior-anterior shift in ageing (PASA) effect.
机译：唤醒和化合价在情绪感知中起关键作用，正常衰老会导致支持化合价处理的神经基质发生变化。这项研究的目的是调查情绪唤醒过程的神经基质中与年龄相关的正常变化。 23名年轻的女性和23名年龄较大的健康女性接受了功能性磁共振成像，因为他们观察的图像中性价或中性价，并且唤醒水平从低到高变化。使用参数调制方法，我们研究了血氧水平依赖性信号如何随单次试验的价和唤醒主观评定而变化，以及其是否随年龄而变化。根据先前的研究，我们发现年龄较大的组在左杏仁核，左颞中回和右舌回中显示出对正价的更大激活。然而，相比之下，他们在双侧枕叶和颞侧视觉皮层，左下顶叶皮层以及双侧运动辅助区中对情绪唤醒的反应性降低。这项研究是同类研究中的第一个，它清楚地揭示了衰老如何影响情绪唤醒和化合价的神经相关性。觉醒过程的变化可能部分由衰老的大脑中明显的功能重组所介导，例如衰老的后向前移位（PASA）效应描述了后皮质的激活减少。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号