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首页> 外文期刊>Neuropsychologia >Distraction during relational reasoning: the role of prefrontal cortex in interference control.
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Distraction during relational reasoning: the role of prefrontal cortex in interference control.

机译：关系推理中的干扰：前额叶皮层在干扰控制中的作用。

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摘要

We compared the reasoning performance of patients with frontal-variant frontotemporal lobar degeneration (FTLD) with that of patients with temporal-variant FTLD and healthy controls. In a picture analogy task with a multiple-choice answer format, frontal-variant FTLD patients performed less accurately than temporal-variant FTLD patients, who in turn performed worse than healthy controls, when semantic and perceptual distractors were present among the answer choices. When the distractor answer choices were eliminated, frontal-variant patients showed relatively greater improvement in performance. Similar patient groups were tested with a relational-pattern reasoning task that included manipulations of one or two relations and both perceptual and semantic extraneous information. Frontal-variant patients showed performance deficits on all tasks relative to the other subject groups, especially when distracted. These results demonstrate that intact prefrontal cortex (PFC) is necessary for controlling interference from perceptual and semantic distractors in order to reason from relational structure.
机译：我们比较了额叶额颞叶大叶变性（FTLD）患者与时变FTLD和健康对照患者的推理表现。在具有多项选择答案格式的图片类比任务中，当在答案选择中存在语义和知觉干扰因素时，额叶变异FTLD患者的表现不如时变FTLD患者，后者表现差于健康人。当消除干扰因素的答案选择时，额叶变异患者表现出相对较大的改善。用关系模式推理任务测试了相似的患者组，该任务包括对一个或两个关系的操作以及感知和语义无关信息。相对于其他受试者组，额叶变异型患者在所有任务上均表现出功能不足，尤其是在分心时。这些结果表明，完整的前额叶皮层（PFC）对于控制来自感知和语义干扰因素的干扰是必要的，以便从关系结构中进行推理。

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