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Functional connectivity during top-down modulation of visual short-term memory representations.

机译:自上而下的视觉短期记忆表示调制过程中的功能连接。

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Recent evidence has revealed that short-lived internal representations held in visual short-term memory (VSTM) can be modulated by top-down control via retrospective attention which impacts subsequent behavioral performance. However, the functional inter-regional interactions underlying these top-down modulatory effects are not fully characterized. Here we used event-related functional magnetic imaging to investigate whether the strength of functional connectivity between the frontal cortex and posterior visual areas varies with the efficacy of top-down modulation of memory traces. Top-down modulation was manipulated by the timing of retro-cuing (early or late) in a VSTM task. Univariate analyses revealed that more effective top-down modulation (early cueing vs. late cueing) increased activity in early visual areas. Importantly, coherency analyses revealed that top-down modulation produced stronger functional connectivity between frontal and posterior occipital regions. Also, participants with stronger functional connectivity exhibit better memory performance. These results suggest that augmented functional connectivity between frontal and posterior visual areas strengthens the VSTM representations of importance to behavioral goals.
机译:最近的证据表明,视觉上的短期记忆(VSTM)中存在的短暂内部表示可以通过自上而下的控制,通过追溯注意力来调节,这会影响后续的行为表现。但是,这些自上而下的调制效应所依据的功能性区域间相互作用尚未得到充分表征。在这里,我们使用事件相关的功能磁成像技术来研究额叶皮质和后视觉区域之间的功能连接强度是否随记忆迹线的自上而下的调制效果而变化。在VSTM任务中,通过回溯(提前或延迟)的时间来控制自上而下的调制。单变量分析表明,更有效的自上而下的调制(早期提示与晚期提示)可以增加早期视觉区域的活动。重要的是,相干分析显示自上而下的调制在额枕和后枕骨区域之间产生了更强的功能连接性。此外,功能连接性更强的参与者表现出更好的记忆性能。这些结果表明,正面和后方视觉区域之间功能的增强连通性增强了对行为目标重要性的VSTM表示。

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