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首页> 外文期刊>Neuroscience Letters: An International Multidisciplinary Journal Devoted to the Rapid Publication of Basic Research in the Brain Sciences >Preganglionic sympathetic neurones, innervating the guinea pig adrenal medulla, immunohistochemically contain choline acetyltransferase and also leu-enkephalin.
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Preganglionic sympathetic neurones, innervating the guinea pig adrenal medulla, immunohistochemically contain choline acetyltransferase and also leu-enkephalin.

机译：神经节神经交感神经元，支配豚鼠肾上腺髓质，免疫组织化学含有胆碱乙酰转移酶和亮脑啡肽。

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摘要

Applying retrograde neuronal tracing combined with double labelling immunofluorescence, preganglionic nerve cell bodies in the intermediate grey matter of the guinea pig thoracic spinal cord, projecting to the adrenal gland, co-exhibited immunolabelling for choline-acetyltransferase (ChAT) and sometimes, also for leu-enkephalin. Likewise, ChAT-immunoreactive nerve fibres, forming a dense meshwork in the adrenal medulla, partly contained immunostaining also for leu-enkephalin. Some of the intramedullary nerve cell bodies were ChAT-positive but were non-reactive for leu-enkephalin. The findings provide evidence for an extrinsic (preganglionic) and an intrinsic (postganglionic) cholinergic nerve system in the guinea pig adrenal medulla, the preganglionic system utilising leu-enkephalin as co-mediator.
机译：应用逆行神经元示踪结合双标记免疫荧光法，将豚鼠胸脊髓中间灰质的神经节前神经细胞体投射到肾上腺，共同展示针对胆碱-乙酰转移酶（ChAT）的免疫标记，有时也用于白细胞-脑啡肽。同样，在肾上腺髓质中形成致密网状结构的ChAT免疫反应性神经纤维也部分含有亮脑啡肽的免疫染色。某些髓内神经细胞体ChAT阳性，但对亮脑啡肽无反应。这些发现为豚鼠肾上腺髓质中神经外系统（神经节前）和内在性（神经节后）胆碱能神经系统提供了证据，神经元前系统利用亮脑啡肽作为共同介体。

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