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首页> 外文期刊>Nigerian Journal of Animal Production >Experimental infections of domestic rabbits ( Oryctolagus cuniculus) with Trypanosoma brucei and Trypanosoma congolense: A comparative study
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Experimental infections of domestic rabbits ( Oryctolagus cuniculus) with Trypanosoma brucei and Trypanosoma congolense: A comparative study

机译：布鲁氏锥虫和锥虫锥虫对家兔家兔实验感染的比较研究

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摘要

Comparative study of single infections of domestic rabbits (Oryctolagus cuniculus) with Mgerian isolates of Trypanosoma brucei (Gboko strain), and Trypanosoma congolense (Binchi strain) was carried out in the laboratory for clinical and haematologicaleffects. Eighteen rabbits of 10-14 weeks old weighing between 600- 1200 grams were used for the study. The rabbits of both sexes were randomly selected and divided into groups. The level of infection was studied by determining total red blood cell (RBC)count, haemoglobin estimation, total and differential white blood cell(WBC) count, changes in body weight, mortality, rectal temperature changes and other clinical signs of trypanosomiasis. There was significant reduction (P< 0.001) in the total red blood cell counts and haemoglobin level in the infected rabbits when compared to the control rabbits with the effect being more pronounced in rabbits infected with T. congolense. The white blood cell count was also highest in those rabbits infecfed with T.congolense. Both parasites produced similar clinical symptoms which included weight loss, unthriftiness, anorexia, fever, paleness of mucous membrane, and oedema of the facial region. One death was recorded in each of the infected group. Possible reasonsfor the significant differences in the total red blood cell count, haemoglobin level, and total white blood cell count are discussed.
机译：在实验室中对家兔（圆孔兔）分别感染了布鲁氏锥虫（Gboko品系）和刚果锥虫（Binchi品系）的Mgerian分离株进行单一感染的比较研究，以进行临床和血液学影响。研究使用了18只10-14周大的兔子，体重在600-1200克之间。随机选择性别的兔子并分成组。通过确定总红细胞（RBC）计数，血红蛋白估计值，总白细胞和差异白细胞（WBC）计数，体重变化，死亡率，直肠温度变化和其他锥虫病临床症状来研究感染水平。与对照兔相比，感染兔的总红细胞计数和血红蛋白水平显着降低（P <0.001），这种效果在被锥虫感染的兔中更为明显。在未感染锥虫的兔子中，白细胞计数也最高。两种寄生虫都产生相似的临床症状，包括体重减轻，节食，厌食，发烧，粘膜苍白和面部区域浮肿。每个感染组均录得一例死亡。讨论了总红细胞计数，血红蛋白水平和总白细胞计数显着差异的可能原因。

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