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Neuroimaging in disorders of cortical development.

机译:皮层发育异常的神经影像学。

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摘要

Malformations of cortical development are important causes of developmental delay and epilepsy. They are classified by the presumed stage during which normal development is interrupted: neuronal proliferation and differentiation, neuronal migration, and late migration/cortical organization. This article discusses the important malformations in each of these groups, how and why the malformations develop, and their imaging findings. A better understanding of these disorders helps in genetic counseling of the parents and may help in the treatment of associated epilepsy.
机译:皮质发育畸形是发育延迟和癫痫的重要原因。根据正常发育中断的假定阶段对它们进行分类:神经元增殖和分化,神经元迁移和晚期迁移/皮层组织。本文讨论了这些组中每个组的重要畸形,畸形的形成方式和原因以及其影像学发现。对这些疾病的更好理解有助于父母的遗传咨询,并可能有助于治疗相关的癫痫。

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