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首页> 外文期刊>Neuroimaging clinics of North America >Flumazenil positron emission tomography and other ligands for functional imaging.
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Flumazenil positron emission tomography and other ligands for functional imaging.

机译:氟马西尼正电子发射断层扫描和其他功能成像配体。

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摘要

Most PET receptor studies in idiopathic generalized epilepsy conducted to date include only small numbers of patients and should be interpreted with caution. Differences between earlier and later studies can largely be explained by different inclusion criteria and improving methodology. The finding of some increase of GABAA receptor binding in IGE has a potential pathologic basis in microdysgenesis.Future studies aiming to elucidate the pathophysiology of IGEs may benefit from the use of subtype-specific opioid ligands, available now, and GABAB ligands, if and when they become available.
机译:迄今为止,在特发性全身性癫痫中进行的大多数PET受体研究仅包括少数患者,应谨慎解释。早期和晚期研究之间的差异可以用不同的纳入标准和改进的方法来解释。在IGE中发现GABAA受体结合的增加可能是微发育异常的潜在病理学基础。旨在阐明IGE病理生理的未来研究可能会受益于使用亚型特异性阿片样物质配体和GABAB配体,无论何时何地他们变得可用。

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