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The clinical epidemiology of multiple sclerosis.

机译:多发性硬化症的临床流行病学。

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A comprehensive knowledge of the natural course and prognosis of multiple sclerosis is of utmost importance for a physician to make it affordable in simple descriptive terms to a patient when personal and medical decisions are to be taken. It is still topical because the currently acknowledged disease-modifying agents only marginally alter the overall prognosis of the disease. It provides reference for evaluating the efficacy of a therapeutic intervention in clinical trials; clues for public health services, health insurance companies, and pharmaceutical industry in their respective activities; and insights into the pathophysiology and the treatment of multiple sclerosis. Precise, consistent, and reliable data from appropriate cohorts have become available and knowledge is fairly comprehensive.
机译:对于医师而言,在要做出个人和医疗决定时,以简单的描述性术语使其能够负担得起,对多发性硬化症的自然病程和预后的全面了解至关重要。这仍然是热门话题,因为当前公认的疾病改良剂只能轻微改变疾病的整体预后。它为评估临床试验中治疗干预的有效性提供参考;公共卫生服务,健康保险公司和制药行业各自活动的线索;以及对多发性硬化症的病理生理学和治疗的见识。来自适当人群的准确,一致和可靠的数据已经可用,并且知识相当全面。

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