• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Neurologia medico-chirurgica. >Utility of fractional anisotropy imaging analyzed by statistical parametric mapping for detecting minute brain lesions in chronic-stage patients who had mild or moderate traumatic brain injury
【24h】

Utility of fractional anisotropy imaging analyzed by statistical parametric mapping for detecting minute brain lesions in chronic-stage patients who had mild or moderate traumatic brain injury

机译：通过统计参数映射分析分数各向异性成像在检测轻度或中度外伤性脑损伤的慢性期患者的微小脑部病变中的作用

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Diffusion tensor imaging (DTI) has recently evolved as valuable technique to investigate diffuse axonal injury (DAI). This study examined whether fractional anisotropy (FA) images analyzed by statistical parametric mapping (FA-SPM images) are superior to T 2*-weighted gradient recalled echo (T2*GRE) images or fluid-attenuated inversion recovery (FLAIR) images for detecting minute lesions in traumatic brain injury (TBI) patients. DTI was performed in 25 patients with cognitive impairments in the chronic stage after mild or moderate TBI. The FA maps obtained from the DTI were individually compared with those from age-matched healthy control subjects using voxel-based analysis and FA-SPM images (p 0.001). Abnormal low-intensity areas on T2*GRE images (T2* lesions) were found in 10 patients (40.0%), abnormal high-intensity areas on FLAIR images in 4 patients (16.0%), and areas with significantly decreased FA on FA-SPM image in 16 patients (64.0%). Nine of 10 patients with T2* lesions had FA-SPM lesions. FA-SPM lesions topographically included most T2* lesions in the white matter and the deep brain structures, but did not include T2* lesions in the cortexear-cortex or lesions containing substantial hemosiderin regardless of location. All 4 patients with abnormal areas on FLAIR images had FA-SPM lesions. FA-SPM imaging is useful for detecting minute lesions because of DAI in the white matter and the deep brain structures, which may not be visualized on T2*GRE or FLAIR images, and may allow the detection of minute brain lesions in patients with post-traumatic cognitive impairment.
机译：弥散张量成像（DTI）最近已发展成为研究弥漫性轴索损伤（DAI）的有价值的技术。这项研究检查了通过统计参数映射分析的分数各向异性（FA）图像（FA-SPM图像）是否优于T 2 *加权梯度召回回波（T2 * GRE）图像或流体衰减反演恢复（FLAIR）图像进行检测创伤性脑损伤（TBI）患者的微小病变。 DTI在25例轻度或中度TBI后的慢性认知障碍患者中进行。使用基于体素的分析和FA-SPM图像，将从DTI获得的FA图分别与年龄匹配的健康对照受试者的FA图进行比较（p <0.001）。在10例患者（40.0％）中发现了T2 * GRE图像上的低强度异常区域（T2 *病变），在4例患者中发现了FLAIR图像上的高强度异常区域（16.0％），并且FA- 16例患者中的SPM图像（64.0％）。 10例T2 *病变患者中有9例患有FA-SPM病变。 FA-SPM病变在地形上包括白质和脑深部结构中的大多数T2 *病变，但不包括皮质/近皮质中的T2 *病变或含有大量含铁血黄素的病变，而无论其位置如何。在FLAIR图像上所有具有异常区域的4例患者均具有FA-SPM病变。 FA-SPM成像可用于检测白质和脑深部结构中的DAI，这在T2 * GRE或FLAIR图像上可能无法显示，因此可用于检测微小病变，并且可能允许对患有后遗症的患者进行微小病变的检测。创伤性认知障碍。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号