Brachial plexus avulsion injury repairs with nerve transfers and nerve grafts directly implanted into the spinal cord yield partial recovery of shoulder and elbow movements.

Bertelli JA; Ghizoni MF

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Brachial plexus avulsion injury repairs with nerve transfers and nerve grafts directly implanted into the spinal cord yield partial recovery of shoulder and elbow movements.

机译：臂丛神经撕脱伤通过神经转移修复，直接将神经移植物植入脊髓可以使肩部和肘部运动部分恢复。

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OBJECTIVE: Complete avulsion of the brachial plexus is a devastating injury that primarily affects young adults. The current treatment is based on nerve transfers, which yield very limited recovery. In this study, brachial plexus injuries were repaired with nerve transfers and nerve grafts directly implanted into the spinal cord. METHODS: Eight patients with complete brachial plexus avulsion injuries were surgically treated. Roots or target nerves of the brachial plexus were repaired with peripheral nerve grafts directly implanted into the spinal cord and with extraplexal nerve transfers. RESULTS: Muscle reinnervation was observed for six patients who received spinal implants. Among those patients, one recovered M4 muscle power. Reinnervation was observed only in proximal upper limb muscles. CONCLUSION: Muscle reinnervation through nerve grafts directly implanted into the spinal cord was demonstrated. It seems that the combination of intra- and extradural neurotizations improves the proximal muscle function results. However, the extent of this improvement is limited and, in our opinion, does not justify the use of spinal implants.

机译：目的：臂丛神经完全撕脱是一种破坏性伤害，主要影响年轻人。当前的治疗是基于神经转移，其恢复非常有限。在这项研究中，通过神经转移和直接将神经移植物植入脊髓来修复臂丛神经损伤。方法：对8例完全性臂丛神经撕脱伤进行手术治疗。臂丛神经的根或目标神经通过直接植入脊髓的周围神经移植物和丛外神经转移修复。结果：6例接受脊柱植入物的患者观察到肌肉神经支配。在这些患者中，一名恢复了M4肌肉力量。仅在上肢近端肌肉中观察到了神经支配。结论：证实了通过直接植入脊髓的神经移植物进行神经支配。硬膜内和硬膜外神经化的组合似乎可以改善近端肌肉功能结果。但是，这种改善的程度是有限的，并且在我们看来，这并不能证明使用脊柱植入物是合理的。

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《Neurosurgery》 |2003年第6期|共6页
作者
Bertelli JA; Ghizoni MF;
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正文语种 eng
中图分类神经病学与精神病学;
关键词
Brachial Plexus; Elbow; Nerve Regeneration; Nerve Transfer; Recovery of Function; 臂丛; 肘; 神经再生; 神经移植; 功能恢复; 肩; 脊髓; 腓肠神经;

机译：Brachial Plexus;Elbow;Nerve Regeneration;Nerve Transfer;Recovery of Function;臂丛;肘;神经再生;神经移植;功能恢复;肩;脊髓;腓肠神经;

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专利

1. Brachial plexus avulsion injury repairs with nerve transfers and nerve grafts directly implanted into the spinal cord yield partial recovery of shoulder and elbow movements. [J] . Bertelli JA, Ghizoni MF Neurosurgery . 2003,第6期

机译：臂丛神经撕脱伤通过神经转移修复，直接将神经移植物植入脊髓可以使肩部和肘部运动部分恢复。
2. Analysis of human acellular nerve allograft combined with contralateral C7 nerve root transfer for restoration of shoulder abduction and elbow flexion in brachial plexus injury: a mean 4-year follow-up [J] . Journal of neurosurgery. . 2020,第6期

机译：人体细胞神经移植与对侧C7神经根转带联合肱骨绑架恢复和肘部神经瘫弯曲弯曲的侵蚀性分析：平均4年后续随访
3. Shoulder function following partial spinal accessory nerve transfer for brachial plexus birth injury. [J] . Grossman JA, Di-Taranto P, Alfonso D, Journal of plastic, reconstructive & aesthetic surgery: JPRAS . 2006,第4期

机译：臂丛神经先天性损伤引起部分脊柱副神经转移后的肩部功能。
4. The Animal Model on Reimplantation of Nerve Root to the Spinal Cord after Root Avulsion of Brachial Plexus in Rats [C] . Pingguang Xia, Liqiang Gu Third International Conference of China on Anatomical Sciences Sep 21-24, 2001 Nantong, China . 2001

机译：大鼠臂丛神经根撕脱伤后神经根再植入脊髓的动物模型
5. Musculoskeletal modeling of the shoulder and elbow in cervical spinal cord injury. [D] . Acosta, Ana Maria. 2002

机译：颈脊髓损伤中肩膀和肘部的肌肉骨骼建模。
6. Transfer of triceps motor branches of the radial nerve to the axillary nerve with or without other nerve transfers provides antigravity shoulder abduction in pediatric brachial plexus injury [O] . Matthew C. McRae, Gregory H. Borschel 2012

机译：with神经肱三头肌运动分支向腋神经的转移（伴有或不伴有其他神经转移）在小儿臂丛神经损伤中提供抗重力肩外展
7. Spinal Accessory Nerve to Triceps Transfer for Recovery of Elbow Extension in Traumatic Brachial Plexus Injuries [O] . Liselotte Bulstra, Nadia Rbia, Femke Mathot, 2017

机译：脊柱辅助神经到Triceps转移，用于创伤性臂丛丛伤中的肘部延伸

Brachial plexus avulsion injury repairs with nerve transfers and nerve grafts directly implanted into the spinal cord yield partial recovery of shoulder and elbow movements.

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