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首页> 外文期刊>Neurosurgery >Patients with spinal cord cavernous malformations are at an increased risk for multiple neuraxis cavernous malformations.
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Patients with spinal cord cavernous malformations are at an increased risk for multiple neuraxis cavernous malformations.

机译：脊髓海绵状畸形的患者发生多发性神经管海绵状畸形的风险增加。

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OBJECTIVE: To determine the prevalence of multiple neuraxis cavernous malformations in patients who initially presented with intramedullary spinal cord (IMSC) cavernous malformations without knowledge of cavernous malformations elsewhere in the neuraxis. METHODS: Hospital records and radiographic files were analyzed for 17 patients who subsequently underwent surgical resection of an IMSC cavernous malformation (histologically proven) and also underwent brain magnetic resonance imaging studies. These 17 patients represented a subset of 32 patients who underwent surgical resection of an IMSC cavernous malformation during the same period. RESULTS: Of 17 patients, 8 (47%) harbored multiple cavernous malformations. This group was composed of five women and three men (mean age, 35.9 yr). There were four Caucasian and four Hispanic patients. CONCLUSION: The prevalence of multiple cavernous malformations in the neuraxis seems to be increased in patients who harbor IMSC cavernous malformations. This finding has important implications for the evaluation and management of these patients and, in some cases, their family members.
机译：目的：确定最初表现为髓内脊髓（IMSC）海绵状畸形但不知道其他地方的海绵状畸形的患者中多发性神经海绵状畸形的患病率。方法：分析了17例患者的医院记录和影像学资料，这些患者随后接受了手术切除的IMSC海绵状畸形（经组织学证实），并且还进行了脑磁共振成像研究。这17例患者代表32例患者的子集，这些患者在同一时期接受了IMSC海绵状畸形的手术切除。结果：在17例患者中，有8例（47％）患有多发性海绵状畸形。该组由五名女性和三名男性组成（平均年龄35.9岁）。有四名白种人和四名西班牙裔患者。结论：携带IMSC海绵状畸形的患者神经内多发性海绵状畸形的患病率似乎有所增加。这一发现对这些患者以及在某些情况下对其家庭成员的评估和管理具有重要意义。

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