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首页> 外文期刊>Neurosurgery >Transient Adenosine-Induced Asystole During the Surgical Treatment of Anterior Circulation Cerebral Aneurysms: Technical Note
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Transient Adenosine-Induced Asystole During the Surgical Treatment of Anterior Circulation Cerebral Aneurysms: Technical Note

机译:前循环脑动脉瘤的手术治疗过程中短暂性腺苷引起的心搏停止:技术说明

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Transient adenosine-induced asystole is a reliable method for pro-oucing a short period of relative hypotension during surgical and endovascular procedures. Although the technique has been described in the endovascular treatment of brain arteriovenous malformations, aortic aneurysms, and posterior circulation cerebral aneurysms, little description of its use in anterior circulation aneurysms is available. OBJECTIVE: To assess the benefits of adenosine-induced transient asystole in complex anterior circulation aneurysms, to describe our experience in selected cases, and to provide the first experience of the use of adenosine in anterior circulation aneurysms. METHODS: The adenosine-induced cardiac arrest protocol allows us to titrate the duration of cardiac arrest on the basis of individual patient responses. The operative setup is the same as with all aneurysm clippings, with the addition of the placement of t'anscutaneous pacemakers as a precaution for prolonged bradycardia or asystole. Escalating doses of adenosine are given to determine the approximate dose that results in 30 seconds of asystole. When requested by the surgeon, the dose of adenosine is administered for definitive dissection and clipping. We present 6 cases in which this technique was used.RESULTS: The use of transient adenosine-induced asystole provided excellent circumferential visualization of the aneurysm neck and safe clip application. All patients did well reurologically and suffered no evidence of perioperative cerebral ischemia or delayed complication from the use of adenosine itself.CONCLUSION: Transient adenosine-induced asystole is a safe and effective technique in select circumstances that may aid in safe and effective aneurysm clipping. Along with the traditional techniques of brain relaxation, skull base approaches, and temporary clipping, adenosine-induced asystole facilitates circumferential visualization of the aneurysm neck and is another technique available to cerebrovascular ...
机译:短暂的腺苷引起的心搏停止是在外科手术和血管内手术中增加短期相对低血压的可靠方法。尽管已经在脑动静脉畸形,主动脉瘤和后循环脑动脉瘤的血管内治疗中描述了该技术,但很少有关于其在前循环动脉瘤中使用的描述。目的:评估腺苷诱导的短暂性心搏过速在复杂前循环动脉瘤中的益处,描述我们在某些病例中的经验,并提供在前循环动脉瘤中使用腺苷的初步经验。方法:腺苷诱导的心脏骤停方案使我们能够根据患者的个人反应来确定心脏骤停的持续时间。手术设置与所有动脉瘤修剪相同,并增加了经皮起搏器的放置,以防止心动过缓或心搏停止过长。给予逐步增加的腺苷剂量以确定导致30秒心搏停止的近似剂量。当外科医生要求时,给予一定剂量的腺苷以进行明确的解剖和修剪。我们目前使用这种技术的6例。结果:使用短暂的腺苷引起的心搏停止提供了很好的动脉瘤颈部的圆周可视化和安全的夹子应用。所有患者的泌尿外科手术均表现良好,并且没有因使用腺苷本身而引起围手术期脑缺血或延迟并发症的迹象。与传统的脑部放松技术,颅底手术方法和临时钳夹技术相结合,腺苷引起的心搏过速促进了动脉瘤颈部的周向可视化,是脑血管疾病的另一种技术。

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