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Ossification of the posterior longitudinal ligament: A review

机译：后纵韧带骨化：综述

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摘要

Ossification of the posterior longitudinal ligament (OPLL) is most commonly found in men, the elderly, and Asian patients. There are many diseases associated with OPLL, such as diffuse idiopathic skeletal hyperostosis, ankylosing spondylitis, and other spondyloarthropathies. Several factors have been reported to be associated with OPLL formation and progression, including genetic, hormonal, environmental, and lifestyle factors. However, the pathogenesis of OPLL is still unclear. Most symptomatic patients with OPLL present with neurological deficits such as myelopathy, radiculopathy, and/or bowel and bladder symptoms. There are some reports of asymptomatic OPLL. Both static and dynamic factors are related to the development of myelopathy. Plain radiography, CT, and MR imaging are used to evaluate OPLL extension and the area of spinal cord compression. Management of OPLL continues to be controversial. Each surgical technique has some advantages and disadvantages, and the choice of operation should be made case by case, depending on the patient's condition, level of pathology, type of OPLL, and the surgeon's experience. In this paper, the authors attempt to review the incidence, pathology, pathogenesis, natural history, clinical presentation, classification, radiological evaluation, and management of OPLL.
机译：后纵韧带（OPLL）的骨化最常见于男性，老年人和亚洲患者。与OPLL相关的疾病很多，例如弥漫性特发性骨骼肥大，强直性脊柱炎和其他脊椎关节病。据报道，有几种因素与OPLL的形成和发展有关，包括遗传，激素，环境和生活方式等因素。但是，OPLL的发病机制仍不清楚。大多数有OPLL症状的患者表现出神经系统缺陷，例如脊髓病，神经根病和/或肠和膀胱症状。有一些无症状OPLL的报告。静态和动态因素都与脊髓病的发展有关。普通射线照相，CT和MR成像用于评估OPLL扩展和脊髓受压面积。 OPLL的管理仍然存在争议。每种外科手术技术都有其优点和缺点，应根据患者的病情，病理水平，OPLL的类型以及外科医生的经验，逐案选择手术方法。在本文中，作者试图回顾OPLL的发生，病理，发病机理，自然病史，临床表现，分类，放射学评估和管理。

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