Use of 5-aminolevulinic acid helps see the way beyond MRI

BergerM.S.

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Use of 5-aminolevulinic acid helps see the way beyond MRI

机译：5-氨基乙酰丙酸的使用有助于探索MRI以外的方法

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Coburger et al.2 present the results of a study in which they demonstrate that 5-aminolevulinic acid (5-ALA) is superior to Gd-DTPA–enhanced intraoperative MRI for histological tumor detection during the course of resection for high-grade gliomas. It doesn't seem to make a difference for metastatic tumors, which is not surprising. With our increasing knowledge that extent of resection significantly impacts not only progression-free survival but also overall survival, we as neurosurgeons are searching for the next biggest impact in patient outcome with our surgical techniques.

机译：Coburger等人[2]提出了一项研究结果，结果表明，在高度神经胶质瘤切除过程中，5-氨基乙酰丙酸（5-ALA）在组织学肿瘤检测方面优于Gd-DTPA增强的术中MRI。似乎对转移性肿瘤没有影响，这不足为奇。随着我们对切除程度的认识不断提高，不仅会影响无进展生存期，而且还会影响整体生存期，作为神经外科医师，我们正在寻求通过手术技术对患者预后产生最大的影响。

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《Neurosurgical focus》 |2014年第2期|共1页
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BergerM.S.;
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1. Use of 5-aminolevulinic acid helps see the way beyond MRI [J] . BergerM.S. Neurosurgical focus . 2014,第2期

机译：5-氨基乙酰丙酸的使用有助于探索MRI以外的方法
2. Diagnostic accuracy of intraoperative perfusion-weighted MRI and 5-aminolevulinic acid in relation to contrast-enhanced intraoperative MRI and C-11-methionine positron emission tomography in resection of glioblastoma: a prospective study [J] . Pala Andrej, Reske Sven N., Eberhardt Nina, Neurosurgical review. . 2019,第2期

机译：术中灌注加权MRI和5-氨基乙酰丙烯酸在胶质母细胞瘤切除中诊断术中灌注加权MRI和5-氨基乙酰丙烯酸的诊断准确性：一项前瞻性研究
3. F-18-Fluorocholine PET/CT, Brain MRI, and 5-Aminolevulinic Acid for the Assessment of Tumor Resection in High-Grade Glioma [J] . Garcia Vicente Ana Maria, Jimenez Aragon Fatima, Villena Martin Maikal, Clinical nuclear medicine . 2017,第6期

机译：F-18-氟化学PET / CT，脑MRI和5-氨基乙酰丙酸，用于评估高级胶质瘤的肿瘤切除术
4. Photodynamic therapy of human skin tumors using topical application of 5-aminolevulinic acid dimethylsulfoxide (DMSO) and edetic acid disodium salt (EDTA) [C] . Author(s): Arie Orenstein M.D. Sheba Medical Ctr. Ramat-Gan Israel, G.Kostenich Sheba Medical Ctr. Tel Hashomer Israel, H.Tsur Sheba Medical Ctr. Tel Hashomer Israel, Photodynamic Therapy of Cancer II . 1995

机译：局部应用5-氨基乙酰丙酸二甲亚砜（DMSO）和乙二胺四乙酸二钠盐（EDTA）的光动力学疗法治疗人皮肤肿瘤
5. Structure-function studies of 5-aminolevulinic acid (ALA) synthases. [D] . Kaganjo, James Chege. 2017

机译：5-氨基乙酰丙酸（ALA）合成酶的结构功能研究。
6. NIMG-06. OUR THERAPEUTIC STRATEGIES FOR GLIOBLASTOMA: INTRAOPERATIVE SUPPORT SYSTEMS INTRAOPERATIVE MRI PET 5-AMINOLEVULINIC ACID (5-ALA) AND NEOADJUVANT CHEMOTHERAPY [O] . Keisuke Miyake, Daisuke Ogawa, Masaki Okada, 2019

机译：nimg-06。我们对胶质细胞瘤的治疗策略：术中支持系统术中MRIPET5-氨基乙酰丙酸（5-ALA）和Neoadjuvant化疗
7. Surgery for Glioblastoma: Impact of the Combined Use of 5-Aminolevulinic Acid and Intraoperative MRI on Extent of Resection and Survival. [O] . Jan Coburger, Vincent Hagel, Christian Rainer Wirtz, 2015

机译：胶质母细胞瘤手术：联合使用5-氨基乙酰丙酸和术中mRI对切除和生存范围的影响。

Use of 5-aminolevulinic acid helps see the way beyond MRI

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