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首页> 外文期刊>Neurosurgical focus >Deep brain stimulation for vocal tremor: a comprehensive, multidisciplinary methodology
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Deep brain stimulation for vocal tremor: a comprehensive, multidisciplinary methodology

机译：深部脑刺激治疗声带震颤：全面的多学科方法

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Tremulous voice is a characteristic feature of a multitude of movement disorders, but when it occurs in individuals diagnosed with essential tremor, it is referred to as essential vocal tremor (EVT). For individuals with EVT, their tremulous voice is associated with significant social embarrassment and in severe cases may result in the discontinuation of employment and hobbies. Management of EVT is extremely difficult, and current behavioral and medical interventions for vocal tremor result in suboptimal outcomes. Deep brain stimulation (DBS) has been proposed as a potential therapeutic avenue for EVT, but few studies can be identified that have systematically examined improvements in EVT following DBS. The authors describe a case of awake bilateral DBS targeting the ventral intermediate nucleus for a patient suffering from severe voice and arm tremor. They also present their comprehensive, multidisciplinary methodology for definitive treatment of EVT via DBS. To the authors' knowledge, this is the first time comprehensive intraoperative voice evaluation has been used to guide microelectrode/stimulator placement, as well as the first time that standard pre- and post-DBS assessments have been conducted, demonstrating the efficacy of this tailored DBS approach.
机译：颤音是许多运动障碍的特征，但当在确诊为原发性震颤的个体中发生时，称为原发性震颤（EVT）。对于患有EVT的人，其颤抖的声音会引起严重的社交尴尬，在严重的情况下可能会导致工作中断和嗜好。 EVT的管理非常困难，并且目前针对声震的行为和医学干预导致效果欠佳。深部脑刺激（DBS）已被提出作为EVT的潜在治疗途径，但是很少有研究能够系统地检查DBS引起的EVT的改善。作者描述了针对严重的声音和手臂震颤的患者，以腹侧中间核为目标的清醒双侧DBS的情况。他们还介绍了通过DBS进行EVT权威治疗的综合，多学科方法。据作者所知，这是首次使用全面的术中声音评估来指导微电极/刺激器的放置，也是首次进行标准的DBS前后评估，证明了这种量身定制的功效。 DBS方法。

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