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首页> 外文期刊>Nordic journal of psychiatry. >Psychotic disorder is an independent risk factor for increased fasting glucose and waist circumference
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Psychotic disorder is an independent risk factor for increased fasting glucose and waist circumference

机译：精神病是空腹血糖和腰围增加的独立危险因素

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Background. Psychosis is associated with excess cardiovascular morbidity and mortality. Aims. To determine the prevalence of cardiovascular risk factors in patients with psychotic disorders compared with the population. Methods. 731 consecutive patients with psychosis recruited from psychiatric outpatient clinics in Stockholm County, Sweden, were compared with 5580 individuals from a population study performed in the same area. The main outcome measures were waist circumference, body mass index (BMI) and fasting glucose. Results. Mean waist circumference in patients vs. controls was for males 106 and 94 cm, respectively, and for females 97 and 85 cm, respectively (P < 0.001); mean fasting glucose in patients vs. controls was for males 5.8 and 5.2 mmol/l, respectively, and for females 5.6 and 4.8 mmol/l, respectively (P < 0.001). Comparisons were controlled for differences in age and family history of diabetes. Increased waist circumference was more common in psychotic patients compared with controls (OR = 3.99; 95% CI 3.09-5.15), controlling for fasting insulin, differences in gender, blood pressure, fasting glucose, family history of diabetes, age and tobacco use. Increased fasting blood glucose was also more common in psychotic patients (OR = 2.41; 95% CI 1.84-3.14) controlling for the same factors with the exception of fasting glucose and with the addition of increased waist circumference. Conclusion. Our study shows that the psychosis illness per se can be considered as a cardiovascular risk factor, independent of the traditional risk factors such as age and smoking.
机译：背景。精神病与过度的心血管发病率和死亡率有关。目的为了确定与人群相比，精神病患者的心血管危险因素的患病率。方法。从瑞典斯德哥尔摩县的精神科门诊诊所招募的731名连续精神病患者与来自同一地区的人口研究的5580名患者进行了比较。主要结果指标是腰围，体重指数（BMI）和空腹血糖。结果。与对照组相比，患者的平均腰围分别为男性106厘米和94厘米，女性97厘米和85厘米（P <0.001）;与对照组相比，患者的平均空腹血糖分别为男性5.8和5.2 mmol / l，女性分别为5.6和4.8 mmol / l（P <0.001）。控制比较，以区分年龄和糖尿病家族史。与对照（OR = 3.99; 95％CI 3.09-5.15）相比，控制空腹胰岛素，性别，血压，空腹血糖，糖尿病家族史，年龄和吸烟的患者，精神病患者的腰围增加更为常见（OR = 3.99; 95％CI 3.09-5.15）。空腹血糖升高在精神病患者中也更为常见（OR = 2.41; 95％CI 1.84-3.14），除了空腹血糖和腰围增加外，控制相同的因素。结论。我们的研究表明，精神病疾病本身可以被视为心血管疾病的危险因素，而与年龄和吸烟等传统危险因素无关。

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