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首页> 外文期刊>Nordic journal of psychiatry. >A prospective study of smoking in young women and risk of later psychiatric hospitalization.
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A prospective study of smoking in young women and risk of later psychiatric hospitalization.

机译:一项关于年轻女性吸烟和以后精神病住院风险的前瞻性研究。

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摘要

BACKGROUND: It is not known whether smoking is a risk factor for mental disorders. Aims: To investigate the prospective associations between cigarette smoking in pregnant women and a range of psychiatric hospital diagnoses. METHOD: Using data from the Copenhagen Perinatal Cohort, we followed a cohort of 7926 young women from 1959-61 to 2007, linking data on cigarette smoking with psychiatric admission diagnoses obtained from the Danish Psychiatric Central Register. The women were interviewed by a physician in 1959-61 when data was obtained on smoking and other health related variables. With adjustment for age, social class and psychopharmacological treatment at baseline, the effects of smoking on the risk of (hierarchically ordered) major categories of mental disorders were examined. RESULTS: Significant positive associations were observed between number of cigarettes smoked and schizophrenia spectrum disorder, substance use-related disorder, a broad category of other non-psychotic disorders, and any psychiatric registration. For affective spectrum disorders, there was a significant, but non-linear association. CONCLUSION: Number of cigarettes smoked in young adulthood significantly predicted a range of psychiatric admission diagnoses and, for most diagnostic categories, evidence of a dose-response relationship was observed.
机译:背景:吸烟是否是精神障碍的危险因素尚不清楚。目的:调查孕妇吸烟与精神科医院诊断的前瞻性关联。方法:使用哥本哈根围产期队列的数据,我们追踪了1959-61年至2007年的7926名年轻女性队列,将吸烟数据与从丹麦精神病学中央登记处获得的精神病入院诊断结果联系起来。在1959-61年间,当获得了有关吸烟和其他与健康相关的变量的数据时,对这些妇女进行了医师采访。在基线时对年龄,社会阶层和心理药物治疗进行了调整后,研究了吸烟对(分层排列的)主要精神疾病风险的影响。结果:吸烟数量与精神分裂症谱系障碍,与物质使用有关的障碍,其他种类的非精神病性障碍以及任何精神科登记之间均存在显着的正相关。对于情感频谱疾病,存在显着但非线性的关联。结论:成年后吸烟的数量显着预测了精神科入院诊断的范围,并且在大多数诊断类别中,观察到剂量-反应关系的证据。

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